Regulation of ATG7 Beclin 1 Program of Autophagic Cell Death by Caspase-8
Description of Invention:
The invention discloses the role of autophagy in regulation cell death. Further it teaches a method of inducing autophagic cell death by administering a caspase inhibitor. The invention also discloses that autophagic cell death can be induced by caspase-8 inhibition and requires the genes ATG7 and Beclin 1.
Inventors:
Michael Lenardo and Yu Li (NIAID) et al.
Patent Status:
DHHS Reference No. E-318-2004/0-US-01 -- U.S. Provisional Application No. 60/556,857 filed 30 May 2004 Licensing Status:
In addition to licensing, the technology is available for further development through collaborative research opportunities with the inventors.
