Diagnostic Reagents And Vaccines For Multiple Genotypes Of Hepatitis C Virus
Description of Invention:
The invention describes the complete nucleotide and deduced amino acid sequences of the envelope 1 (E1) gene of 51 hepatitis C virus (HCV) isolates from around the world and the grouping of these isolates into twelve distinct HCV genotypes. More specifically, this invention relates to the oligonucleotides, peptides and recombinant proteins derived from the envelope 1 gene sequences of these isolates and to diagnostic methods and vaccines that employ these reagents.
Inventors:
J Bukh (NIAID) RH Miller (NIAID) RH Purcell (NIAID)
Patent Status:
U.S. Patent 5,514,539 issued 07 May 1996 (DHHS Reference No. E-120-1993/0-US-01)
U.S. Patent 5,871,962 issued 16 Feb 1999 (DHHS Reference No. E-120-1993/0-US-04)
U.S. Patent 6,572,864 issued 03 Jun 2003 (DHHS Reference No. E-120-1993/0-US-03)
For Additional Information Please Contact: Susan Ano Ph.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-5515
Email: anos@mail.nih.gov
Fax: (301) 402-0220
