Treatment Option Overview
Key Points for This Section
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There are different types of treatment for patients with breast cancer.
Different types of treatment are available for patients with breast
cancer. Some treatments are standard (the currently used treatment), and some
are being tested in clinical trials.
A treatment clinical trial is a research study meant to help
improve current treatments or obtain information on new treatments for patients
with cancer. When clinical trials show that a new treatment is better than the
standard treatment, the new
treatment may become the standard treatment.
For some patients, taking part in a clinical trial may be the best treatment choice. Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.
Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.
Clinical trials are taking place in many parts of the country.
Information about clinical trials is available from the
NCI Web site.
Treatment options for pregnant women depend on the stage of the
disease and the age of the fetus.
Three types of standard treatment are used:
Surgery
Most pregnant women with breast cancer have surgery to remove the breast. Some of the lymph
nodes under the arm are usually taken out and looked at under a
microscope to see if they contain cancer cells.
Types of surgery to remove the breast include:
- Simple
mastectomy: A surgical procedure to remove the whole breast that contains cancer. Some of the lymph nodes under the arm may also be removed for biopsy. This procedure is also called a total mastectomy.
Enlarge | | | Total (simple) mastectomy. The dotted line shows where the entire breast is removed. Some lymph nodes under the arm may also be removed. |
- Modified radical
mastectomy: A surgical procedure to remove the whole breast that has cancer, many of the lymph nodes under the arm, the lining over the chest muscles, and sometimes, part of the chest wall muscles.
Enlarge | | | Modified radical mastectomy. The dotted line shows where the entire breast and some lymph nodes are removed. Part of the chest wall muscle may also be removed. |
Breast-conserving
surgery, an operation to remove the cancer but not the breast
itself, includes the following:
- Lumpectomy:
A surgical procedure to remove a tumor (lump) and a small amount of normal tissue around it.
Most doctors also take out some of the lymph nodes under the arm.
- Partial mastectomy: A surgical procedure to remove the part of the breast that contains cancer and some normal tissue around it. Some of the lymph nodes under the arm may also be removed for biopsy. This procedure is also called a segmental mastectomy.
Enlarge
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Breast-conserving surgery. Dotted lines show the area containing the tumor that is removed and some of the lymph nodes that may be removed. |
Even if the doctor removes all of the cancer that can be seen at
the time of surgery, the patient may be given radiation therapy, chemotherapy, or hormone therapy after surgery to try
to kill any cancer cells that may be left. Treatment given after surgery to
increase the chances of a cure is called adjuvant
therapy.
Radiation therapy
Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells. There are two types of radiation therapy. External radiation therapy uses a machine outside the body to send radiation toward the cancer. Internal radiation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer. The way the radiation therapy is given depends on the type and stage of the cancer being treated.
Radiation therapy should not be given to pregnant women with early stage (stage I or II) breast cancer because it can harm the fetus. For women with late stage (stage III or IV) breast cancer, it should not be given during the first 3 months of pregnancy.
Chemotherapy
Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping the cells from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the spinal column, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated.
Chemotherapy should not be given during the first 3 months
of pregnancy. Chemotherapy given after this time does not usually harm the
fetus but may cause early labor and
low birth weight.
New types of treatment are being tested in clinical trials.
This summary section describes treatments that are being studied in
clinical trials. It may not mention every new treatment being studied.
Information about clinical trials is available from the
NCI Web site.
Hormone therapy
Hormone therapy is a cancer treatment that removes hormones or blocks their action and stops cancer cells from growing. Hormones are substances produced by glands in the body and circulated in the bloodstream. Some hormones can cause certain cancers to grow. If tests show that the cancer cells have places where hormones can attach (receptors), drugs, surgery, or radiation therapy are used to reduce the production of hormones or block them from working.
The effectiveness of hormone therapy, alone or combined with chemotherapy, in
treating breast cancer in pregnant women is not yet known.
Ending the pregnancy does not seem to improve the mother’s
chance of survival and is not usually a treatment option.
If the cancer must be treated with chemotherapy and radiation therapy, which may harm the
fetus, ending the pregnancy is
sometimes considered. This decision may depend on the stage of cancer, the age
of the fetus, and the mother’s chance of survival.
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