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Environmental Lung Disease Center (National Jewish Medical and Research Center)

National Jewish Medical and Research Center

The objectives of the Environmental Lung Disease Center are to improve the understanding of lung disease, and develop innovative early disease detection, prevention and treatment approaches. The center's research involves: 1) determining the molecular mechanisms of environmental and occupational lung disease, 2) identifying the genetic and molecular basis for individual susceptibility, and 3) identifying the risk and effects of air pollution on human population with preexisting pulmonary diseases, and the exposure/host response relationship that leads to disease. Besides immunologic diseases, the project will focus on respiratory, allergic, and infectious diseases, through an integrated program of basic and clinical research.

Center Publications:

View Projects in List Format

	Identifier	Abstract	Principal Investigator	Annual/ Final Reports	Pubs Count	Institution	Grant Representative	Grant Amount	Project Period
1	R825275 Grant	Asthma Indices Associated with Ambient Submicron Particles and Formaldehyde in Ambient Air Pollution	Fennelly, Kevin P. Anderson, Larry G. Bartelson, Becki	Final	Total Pubs: 2 -- No Journals -- -- No Books --	National Jewish Medical and Research Center	Katz, Stacey Robarge, Gail	$178,865	December 1996 - November 1997
2	R825702 Centers - Main center abstract - Environmental Lung Disease Center (National Jewish Medical and Research Center)	Immunologic Basis of Environmental Lung Disease	Mason, Robert J. Gelfand, Erwin Rabinovitch, Nathan White, Carl W. - Principal Investigators listed are sub-PIs determined by the center.	Final	Total Pubs: 59 Journals: 38 -- No Books --	National Jewish Medical and Research Center	Glenn, Barbara	$7,269,177	February 1998 - February 2003
3	R825702C001 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	SP-A and SP-D in Environmental Lung Disease	Mason, Robert P. Cook, James L. Voelker, Dennis R. - Principal Investigators listed are sub-PIs determined by the center.	Final	Total Pubs: 12 Journals: 10 -- No Books --	National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Glenn, Barbara	Refer to main center abstract for funding details.	February 1998 - February 2003
4	R825702C003 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Adaptation to Nitrogen Dioxide: Role of Altered Glycolytic Pathway Enzyme Expression and NF-κB-Dependent Cellular Defenses Against Apoptosis	White, Carl W. Cook, James L. - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
5	R825702C005 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Inhalation of Particulate Matter Alters the Allergic Airway Response to Inhaled Allergen	Gelfand, Erwin Borish, Larry - Principal Investigators listed are sub-PIs determined by the center.	Final		National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Glenn, Barbara	Refer to main center abstract for funding details.	February 1998 - February 2003
6	R825702C006 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Particle-Induced Lung Inflammation and Extracellular EC-SOD	Crapo, James D. Chang, Ling-Yi - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
7	R825702C007 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Indoor-Outdoor Relationships of Airborne Particle Count and Endotoxin Concentrations	Fennelly, Kevin P. - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
8	R825702C008 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	The Role of Mitochondrial DNA Mutations in Oxidant-Mediated Lung Injury	Day, Brian - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
9	R825702C009 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Immunopathogenesis of Hypersensitivity Pneumonitis in the Mouse	Routes, John M. Borish, Larry - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
10	R825702C010 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Activation of Natural T Lymphocytes by Diesel Exhaust Particulates Leads to Their Production of Interleukin-4 and TH2 Lymphocyte Differentiation to Allergen	Routes, John M. Borish, Larry - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
11	R825702C011 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Latex Antigen Levels During Powdered and Powderless Glove Use	Balkissoon, Ron Westcott, Jay - Principal Investigators listed are sub-PIs determined by the center.			National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Katz, Stacey	Refer to main center abstract for funding details.	February 1998 - February 2003
12	R825702C012 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Adjuvant Effects of Ozone in a Model of Allergen-Induced Airway Inflammation and Hyperresponsiveness	Mason, Robert J. Gelfand, Erwin - Principal Investigators listed are sub-PIs determined by the center.	Final	Total Pubs: 24 Journals: 20 -- No Books --	National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Glenn, Barbara	Refer to main center abstract for funding details.	February 1998 - February 2003
13	R825702C013 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Acute Exposure to Particulate Air Pollution in Childhood Asthma	Chang, Ling-Yi Rabinovitch, Nathan Gelfand, Erwin - Principal Investigators listed are sub-PIs determined by the center.	Final	Total Pubs: 20 Journals: 5 -- No Books --	National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Glenn, Barbara	Refer to main center abstract for funding details.	February 1998 - February 2003
14	R825702C014 Centers - This is a subproject of the Environmental Lung Disease Center (National Jewish Medical and Research Center)	Mechanisms of Ozone Toxicity to the Lung	White, Carl W. Murphy, Robert C. - Principal Investigators listed are sub-PIs determined by the center.	Final	Total Pubs: 3 Journals: 3 -- No Books --	National Jewish Medical and Research Center	EPA Project Officer(s) for Environmental Lung Disease Center (National Jewish Medical and Research Center) Grant Number R825702: Glenn, Barbara	Refer to main center abstract for funding details.	February 1998 - February 2003

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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