Los Alamos HIV Drug Resistance Database

IMPORTANT: This site is no longer maintained. Due to lack of funds, the HIV resistance database is no longer being updated; the last update was done in 2007. We initially planned to remove it on Dec 31, 2008, but after several email requests it will stay up until July 1, 2009. After that, it will only be available on request as a tab-delimited text file.

The database is a compilation of mutations in HIV genes that confer resistance to anti-HIV drugs. To begin a search simply fill out the search form and press the "Start Search" button. The resulting list of records that match your search parameters is displayed as a table. The table does not show all the fields for each record (for example, most bibliographic information is not shown). To see a detailed view about a particular record click on the leftmost field (Gene) which is an active link to the detailed view in which all information is displayed.
DISCLAIMER

Simple Search

The Simple Search option allows you to search the database by gene, compound, drug class, and amino acid position only.

Advanced Search

The Advanced Search includes most fields in the database.

Browse

The Browse link displays all the records in the database sorted by gene in genomic order, and within each gene by amino acid position. When browsing you may resort the records any way you chose, such as by drug compound.

ADRA

Antiviral Drug Resistance Analysis. This program analyzes your sequences for mutations known to confer drug resistance and links to the records in the database.

Maps & 3D Proteins

We have begun mapping the mutations in protease and have organized them by compound. Use this map to find your drug and mutation of interest and then click on it to link to that record in the database.

An interface that presents a 3-D image of protease or RT with your choice of amino acid positions highlighted.

Links

Click here for a listing of fields in this database.

Stanford HIV drug resistance database stores and analyzes data underlying HIV drug resistance.

HIV Structural Database and Chem-BLAST at NIST.

HIV glossary kindly compiled by "thebody.com".

Credits

Listing of authors who maintain this site

IMPORTANT: This site is no longer maintained. Due to lack of funds, the HIV resistance database is no longer being updated; the last update was done in 2007. We initially planned to remove it on Dec 31, 2008, but after several email requests it will stay up until July 1, 2009. After that, it will only be available on request as a tab-delimited text file. The database is a compilation of mutations in HIV genes that confer resistance to anti-HIV drugs. To begin a search simply fill out the search form and press the "Start Search" button. The resulting list of records that match your search parameters is displayed as a table. The table does not show all the fields for each record (for example, most bibliographic information is not shown). To see a detailed view about a particular record click on the leftmost field (Gene) which is an active link to the detailed view in which all information is displayed. DISCLAIMER
Simple Search	The Simple Search option allows you to search the database by gene, compound, drug class, and amino acid position only.
Advanced Search	The Advanced Search includes most fields in the database.
Browse	The Browse link displays all the records in the database sorted by gene in genomic order, and within each gene by amino acid position. When browsing you may resort the records any way you chose, such as by drug compound.
ADRA	Antiviral Drug Resistance Analysis. This program analyzes your sequences for mutations known to confer drug resistance and links to the records in the database.
Maps & 3D Proteins	We have begun mapping the mutations in protease and have organized them by compound. Use this map to find your drug and mutation of interest and then click on it to link to that record in the database. An interface that presents a 3-D image of protease or RT with your choice of amino acid positions highlighted.
Links	Click here for a listing of fields in this database. Stanford HIV drug resistance database stores and analyzes data underlying HIV drug resistance. HIV Structural Database and Chem-BLAST at NIST. HIV glossary kindly compiled by "thebody.com".
Credits	Listing of authors who maintain this site