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Thursday, September 11, 2008 |
Volume
21 Number 11 |
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This weekly update provides information about the impact of human genomic research on disease prevention & population health. |
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Obesity and Genetics
Obesity is a major health hazard that has reached epidemic proportions in populations whose environments offer an abundance of calorie-rich foods and few opportunities for physical activity. Though population genetic changes are too slow to be blamed for the increase in obesity, genes play a role in the development of obesity. Read more |
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- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
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Cancer |
Genetic region linked to a 5 times higher lung cancer risk, Medical News Today, September 10 |
Genome lights the way to cancer 'milestone', Baltimore Sun, September 5 |
Early stage colon cancer characterized by inactivation of gatekeeper gene, Singapore... , Medical News Today, September 10 |
The cancer genome atlas reports first results of comprehensive study of brain tumors, NIH News, September 4 |
Lung cancer risk models created for specific populations, prediction refined, Medical News Today, September 8 |
Gene trawl shows curing cancer harder than thought, Reuters Health, September 4 |
Study: Family history may leave African-Americans unscreened, The JHU Gazette, September 8 |
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Other News |
Genetic mutation prevents fetal malaria transmission, study says, News-Medical.Net, September 11 |
Variety in the splice of life: Chromosome breaks are surprisingly complex, Medical News Today, September 9 |
Symposium: How do race, genetics and health-care disparities affect spread of HIV, Medical News Today, September 11 |
Genetic screening could help thousands, Wales Online, September 8 |
Virus is passed from parent to child in the DNA, Reuters Health, September 4 |
Lab to detect genetic defects in newborns, The Times of India, September 8 |
First Of 100 Arab Human Genomes sequenced by Saudi Biosciences, Beijing Genomics Institute..., Medical News Today, September 10 |
Valley family battling rare genetic disease, WAFF 48 News, September 8 |
Genetic variants associated with vitamin B12, Science Daily, September 9 |
Framing the concept of a gene, News-Medical.Net, September 4 |
Safety study indicates gene therapy for blindness improves vision, Medical News Today, September 9 |
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Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays
Homer N, et al.
PLoS Genet. 2008 Aug 29;4(8):e1000167
Protecting Aggregate Genomic Data
Zerhouni EA & Nabel EG
Science 2008 Sep
An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment
Ekhart C, et al.
Cancer Treat Rev 2008 Sep
A joint association test for multiple SNPs in genetic case-control studies
Wang T, et al.
Genet Epidemiol 2008 Sep
The FBN2 gene: new mutations, locus-specific database (Universal Mutation Database FBN2), and genotype-phenotype correlations
Frederic MY, et al.
Hum Mutat 2008 Sep
Stratification for smoking in case-cohort studies of genetic polymorphisms and lung cancer
Sorensen M, et al.
Lung Cancer 2008 Sep
Germline Polymorphisms as Modulators of Cancer Phenotypes
Tan P
BMC Med 2008 Sep;6(1):27
Genomic Variation in Myeloma: Design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression free survival
Van Ness B, et al.
BMC Med 2008 Sep;6(1):26
Ethics of Future Disclosure of Individual Risk Information in a Genetic Cohort Study: A Survey of Donor Preferences
Matsui K, et al.
J Epidemiol 2008 Sep
The Stigmatising Implications of Presenting Schizophrenia as a Genetic Disease
Bennett L, et al.
J Genet Couns 2008 Sep
Can genes for mammographic density inform cancer aetiology?
Kelemen LE, et al.
Nat Rev Cancer 2008 Sep
Genes in asthma: new genes and new ways
Moffatt MF
Curr Opin Allergy Clin Immunol 2008 Oct;8(5):411-7
Genomics: risk and outcomes in cardiac surgery
Perry TE, et al.
Anesthesiol Clin 2008 Sep;26(3):399-417
Genetics of headache in children: where are we headed?
Hershey AD
Curr Pain Headache Rep 2008 Oct;12(5):367-72
Heritability of the severity of diabetic retinopathy: the FIND-Eye study
Arar NH, et al.
Invest Ophthalmol Vis Sci 2008 Sep;49(9):3839-45
Psychiatric disorder in young adults born very preterm: Role of family history
Walshe M, et al.
Eur Psychiatry 2008 Sep
Attitudes toward genetic testing and personalised nutrition in a representative sample of European consumers
Stewart-Knox BJ, et al.
Br J Nutr 2008 Sep:1-8
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer Gudmundsson J, Sulem P, Rafnar T, Bergthorsson JT, Manolescu A, Gudbjartsson D, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Blondal T, Jakobsdottir M,
Stacey SN, Kos
Brooks J
Urol Oncol 2008 Sep-2008 Oct;26(5):569-70
Multiple newly identified loci associated with prostate cancer susceptibility Eeles RA, Kote-Jarai Z, Giles GG, Olama AA, Guy M, Jugurnauth SK, Mulholland S, Leongamornlert DA, Edwards SM, Morrison J, Field HI, Southey MC, Severi G, Donovan JL, Hamdy
Brooks J
Urol Oncol 2008 Sep-2008 Oct;26(5):570
Common variants of FUT2 are associated with plasma vitamin B(12) levels
Hazra A, et al.
Nat Genet 2008 Sep
Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study
Liu YZ, et al.
PLoS ONE 2008;3(9):e3160
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Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page
For the week ending September 10, 2008, there are HuGE articles in the following areas:
Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions
For more information on HuGE, please visit the HuGENet™ home page
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The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing
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Provides link to non-governmental sites and does not necessarily represent the views of the Centers for Disease Control and Prevention. |
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