Gene Knockout/Transgenic Mice
NIAID Exchange Program


To foster increased availability to the scientific community of immunologically-related, gene-targeted mouse strains, the National Institute of Allergy and Infectious Diseases (NIAID) has instituted a special partnership with Taconic Farms, Inc., called the NIAID Exchange Program. The costs of this Program are partially underwritten by NIAID funds to provide ready access to emerging mouse models. The strains chosen for the Exchange Program are selected by the NIAID Mouse Repository Committee based on expected interest to the scientific community and degree of genetic standardization and phenotypic characterization. The 21 strains currently available are:

  • [KO]gc chain and [KO]Rag2, C57BL/6xC57BL/10SgSnAi bkg

  • [KO]Nos2, C57BL/6Ai bkg C57BL/6-[KO]iNOSN9

  • B10.D2-[TG] TCR DO11.10-[KO]RAG2 N10,N2

  • B10.A-[TG]5CC7-1-[KO]RAG2 N12

  • C57BL/10-[KO]gc-[KO]RAG2 N9, N1

  • C57BL/10-[TG] TCR P14 LCMV-[KO]RAG2 N11

  • C57BL/6-[TG]MHC hu DR-4 a1b1-[KO]Abb

  • BALB/c-IL4Ra[KO]

  • B6-CD4-Cre

  • B6-lck Cre

  • B6-Flt3[KO]

  • B6-IL15[KO]

  • BALB/c-[TG]DO11.10-[KO]RAG2

  • B7-[TG] OT_I-[KO]RAG1

  • B6-[KO]PHOX

  • B10-[TG] P14 LCMV-[KO] TCRa

  • B6-[KO] CCR1

  • B6-[KO]Db-[KO] Kb

  • B6-[KO] Kb

  • B6-[KO] Db

  • B10.D2

  • B6.SJL

For more information, contact Taconic at TaconicSer@aol.com or at 518-537-6208, or access the Taconic Emerging Models Site: http://www.taconic.com/emerging/listing.htm.


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