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Nasopharyngeal Cancer Treatment (PDQ®)
Patient Version   Health Professional Version   En español   Last Modified: 07/09/2008



Purpose of This PDQ Summary






General Information About Nasopharyngeal Cancer






Cellular Classification of Nasopharyngeal Cancer






Stage Information for Nasopharyngeal Cancer






Treatment Option Overview






Stage I Nasopharyngeal Cancer






Stage II Nasopharyngeal Cancer






Stage III Nasopharyngeal Cancer






Stage IV Nasopharyngeal Cancer






Recurrent Nasopharyngeal Cancer






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Changes to This Summary (07/09/2008)






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Past Highlights
Stage II Nasopharyngeal Cancer

Current Clinical Trials

Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.)

Standard treatment options:

  1. Chemoradiation therapy.[1][Level of evidence: 3iiiA]


  2. High-dose radiation therapy to the primary tumor site and prophylactic radiation therapy to the nodal drainage.[2-4]


Current Clinical Trials

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage II nasopharyngeal cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

References

  1. Cheng SH, Tsai SY, Yen KL, et al.: Concomitant radiotherapy and chemotherapy for early-stage nasopharyngeal carcinoma. J Clin Oncol 18 (10): 2040-5, 2000.  [PUBMED Abstract]

  2. Mesic JB, Fletcher GH, Goepfert H: Megavoltage irradiation of epithelial tumors of the nasopharynx. Int J Radiat Oncol Biol Phys 7 (4): 447-53, 1981.  [PUBMED Abstract]

  3. Hoppe RT, Goffinet DR, Bagshaw MA: Carcinoma of the nasopharynx. Eighteen years' experience with megavoltage radiation therapy. Cancer 37 (6): 2605-12, 1976.  [PUBMED Abstract]

  4. Mendenhall WM, Riggs CE Jr, Cassisi NJ: Treatment of head and neck cancers. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds.: Cancer: Principles and Practice of Oncology. 7th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2005, pp 662-732. 

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