2006 Annual Report 4d.Progress report. This report serves to document research conducted under a specific cooperative agreement between ARS and The North American Millers Association. The objectives were in support of the long-term goal of the parent CRIS, 5348-21220-003-00D, Identification and Deployment of Genes to Reduce Production Risks and Improve Quality in Club and Soft White Winter Wheat. Collaborative research to implement marker assisted selection in plant breeding for disease resistance. 20 new soft white breeding lines with combined resistance and improved quality have been developed by Dr. Garland Campbell using marker assisted selection. The problem is that implementation of biotech tools like marker assisted selection has been slow to be adopted in wheat breeding programs. The genotyping lab continues to upgrade to high throughput equipment but has provided over 12,000 data-points to collaborators in the Western Region in 2005 and 13,623 data-points to collaborators from Jan. to June 2006. Those data-points have used to improve efficiencies in selection of improved soft and hard spring and winter wheat cultivars and barley cultivars for the western region of the US.