Topotecan Hydrochloride This page contains brief information about topotecan hydrochloride and a collection of links to more information from the National Cancer Institute (NCI), the Food and Drug Administration (FDA), and the National Library of Medicine (NLM). US Brand Name(s): | ![](https://webarchive.library.unt.edu/eot2008/20080920120954im_/http://www.cancer.gov/images/spacer.gif) | Hycamtin | ![](https://webarchive.library.unt.edu/eot2008/20080920120954im_/http://www.cancer.gov/images/spacer.gif) | ![](https://webarchive.library.unt.edu/eot2008/20080920120954im_/http://www.cancer.gov/images/spacer.gif) | FDA Approved: | ![](https://webarchive.library.unt.edu/eot2008/20080920120954im_/http://www.cancer.gov/images/spacer.gif) | Yes |
Topotecan hydrochloride is approved by the Food and Drug Administration (FDA) to treat ovarian cancer and small cell lung cancer in patients whose cancer has not gotten better with earlier chemotherapy. It is also approved to be used together with another medicine, called cisplatin, to treat cervical cancer in some women whose cancer has not gotten better or has recurred (come back).
Topotecan hydrochloride is also being studied in the treatment of other types of cancer. Information from the FDA
FDA Approval for Topotecan Hydrochloride - Information from the FDA about the approval of this drug and the clinical trials that led to the approval.
Information from the NCIDefinition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
Clinical Trial Results: Topotecan and Advanced Cervical Cancer (08/17/2005) - Important clinical trial results for this drug, background information, and how the trial was done.
Information from the NLM
MedlinePlus Information on Topotecan Hydrochloride - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied. Clinical TrialsClinical Trials for Topotecan Hydrochloride - Check for trials from NCI's PDQ Cancer Clinical Trials Registry now accepting patients.
Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.
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