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Atrazine Interim Reregistration Eligibility Decision (IRED) Q&A's - January 2003

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Q & A's

EPA is completing its interim reregistration eligibility decision (IRED) for the pesticide atrazine, a herbicide primarily used to control broadleaf and some grassy weeds for a variety of major and minor crops and nonagricultural uses. First registered in 1958, and used extensively throughout the country, atrazine is being reviewed as part of EPA’s program to ensure that older pesticides meet current health and environmental safety standards. As part of this effort, EPA has reviewed an extensive body of data and studies, conferred with independent scientific experts in a variety of disciplines, and encouraged public and stakeholder participation. The IRED document identifies the various conditions and risk mitigation measures necessary to ensure that approved uses of atrazine meet federal safety standards. EPA prepared this document after close consultation with our federal, state, and tribal regulatory partners. This Q&A document provides technical and general information about atrazine and its current regulatory status under pesticide and water laws.

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  1. What is atrazine and how is it used?
  2. Where is atrazine used most heavily?
  3. What are atrazine’s potential effects on human health?
  4. What action is EPA currently taking with atrazine?
  5. How did EPA come to this decision?
  6. How many community water systems are there, and how many are we concerned about?
  7. What are the new and innovative measures being implemented as part of the IRED?
  8. In which states are there watersheds where intensive monitoring going to begin now?
  9. Does this IRED address endangered species issues?
  10. Why is EPA taking this action now?
  11. What are the public health benefits we expect from this action related to drinking water?
  12. Are there other health benefits to be gained from this action?
  13. What are the environmental benefits we expect from this action?
  14. What about atrazine in rural well water - will monitoring assure that all home wells are O.K.?
  15. Recent studies and journals have raised new concerns regarding the potential effects of atrazine on frogs. Does the IRED address potential amphibian (frog) risk?

  1. What is atrazine and how is it used?
  2. Atrazine, which may be applied both before and after planting to control broadleaf and grassy weeds, was first registered for use as a herbicide on December 1, 1958. Atrazine is currently one of the most widely used agricultural pesticides in the United States, with estimated production of 76 to 85 million pounds annually. Approximately 76.5 million pounds of active ingredient are applied domestically per year. The main use sites for applying atrazine include the following:

    Agricultural sites:

    Non-agricultural sites:


  3. Where is atrazine used most heavily?
  4. Atrazine is estimated to be the most heavily used herbicide in the United States. Its primary uses are on corn and sugarcane and on residential lawns in Florida and the Southeast. Currently, the heaviest atrazine uses per unit area occur in portions of Delaware, Iowa, Illinois, Indiana, Ohio, and Nebraska.


  5. What are atrazine’s potential effects on human health?
  6. In EPA’s refined risk assessment, issued in May 2002, the Agency reviewed extensive data relating to the potential human health effects of atrazine exposure. EPA found, in consultation with an independent scientific advisory panel, that it is not likely to be carcinogenic to humans. However, there is concern that atrazine has been associated with causing imbalances in hormone levels in laboratory animals, possibly disrupting reproductive and developmental processes. EPA considered these effects, and the exposure levels that created such concerns, in determining what types of risk mitigation measures are necessary to meet Federal safety standards.

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  7. What action is EPA currently taking with atrazine?
  8. EPA is completing its Interim Reregistration Eligibility Decision (IRED) for the pesticide atrazine, outlining the label changes and risk reduction steps necessary for the pesticide to meet health and environmental safety standards under EPA’s pesticide reregistration program. This program ensures that older pesticides meet current health and environmental safety standards. In developing this decision, EPA conducted a comprehensive scientific review of atrazine’s use, risks, and benefits, and sought frequent input from the broader scientific community. EPA sought public comment and participation throughout the process, and conducted extensive consultations with its federal, state, and local regulatory partners, the registrant community, the affected pesticide user communities, public interest groups, and other stakeholders.

  9. How did EPA come to this decision?
  10. This is the latest step in a process to review atrazine and other older pesticides against current standards. The process includes updating available data on the pesticide being reviewed. To date, EPA has completed the following steps as part of the atrazine review.


  11. How many community water systems are there, and how many are we concerned about?
  12. There are approximately 50,000 community drinking water systems in the United States. Of these, 40,000 are served by ground water, and 10,000 are served by surface water.

    Surface water is our focus in this action. For the 10,000 community water systems served by surface water, the Agency has identified 3,600 systems where atrazine is used and monitoring information is available.

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  13. What are the new and innovative measures being implemented as part of the IRED?
  14. Human Health Measures

    The IRED includes measures to address risks to workers, risks associated with residential uses, and risks from drinking water. EPA has put in place enforceable requirements, including:

    In addition, to confirm that rural drinking water wells are not expected to have atrazine levels that exceed the Agency's level of concern, the Agency will require that the registrant(s) conduct a rural well monitoring study in atrazine use areas.

    EPA also is requiring changes to better protect workers and people who may be exposed to atrazine used in residential settings.

    Ecological Measures

    To mitigate risks to the environment from atrazine residues, the Agency is establishing a tiered ecological assessment process that will identify waterbodies affected by atrazine and determine which of these waterbodies are candidates for atrazine monitoring and/or mitigation. Waterbodies that may be identified for mitigation are waters officially listed by a state as impaired and/or waters with measured exceedences of the Agency's level of concern. Monitoring programs to determine if mitigation is required may be based on such factors as frequency, duration, and level of atrazine concentrations; atrazine use in the watershed; and environmental vulnerability. The plan will be completed in spring 2003.

  15. In which states are there watersheds where intensive monitoring going to begin now?
  16. EPA has identified approximately 200 community water systems in the following states where monitoring will begin now: Alabama, Ohio, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Michigan, Missouri, Texas.

  17. Does this IRED address endangered species issues?
  18. The ecological assessment is the baseline of information from which we conduct our assessment specific to threatened and endangered species. Although some uses of atrazine have been assessed and consulted on in the past, an updated endangered species assessment will follow completion of the ecological assessment. The measures in the IRED will serve as protective measures in the interim.

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  19. Why is EPA taking this action now?
  20. EPA has long considered its review of atrazine to be a high priority in the reregistration and tolerance reassessment program, and has been working to complete the scientific analysis and public consultation necessary to release a well-grounded decision as quickly as possible. In addition, EPA agreed in a Consent Decree with a number of public interest groups to complete this portion of the atrazine review by January 31, 2003.


  21. What are the public health benefits we expect from this action related to drinking water?
  22. By implementing an intensive monitoring program when certain levels of atrazine are detected in water supplies, and by prohibiting atrazine uses in watersheds that result in exceedences, EPA will be able to ensure that exposures to atrazine in drinking water do not reach levels that pose a risk to public health. The study of rural wells will similarly provide a level of assurance that unacceptable exposure to atrazine is not occurring by this means.


  23. Are there other health benefits to be gained from this action?
  24. Other measures included in the IRED, such as changes to the way atrazine is handled and its use in residential settings, including reducing application rates, changing the application method to spot treatments, and requiring that grass be watered after application. Label changes for residential use, which take effect in 2004, will reduce potential exposure and risk to workers and people in residential situations.


  25. What are the environmental benefits we expect from this action?
  26. To mitigate risks to the environment from atrazine residues, the Agency is establishing a tiered ecological assessment process that will identify waterbodies affected by atrazine and determine which of these waterbodies are candidates for atrazine monitoring and/or mitigation. Waterbodies that may be identified for mitigation are waters officially listed by a state as impaired and/or waters with measured exceedences of the Agency's level of concern. Monitoring programs to determine if mitigation is required may be based on such factors as frequency, duration, and level of atrazine concentrations; atrazine use in the watershed; and environmental vulnerability.

  27. What about atrazine in rural well water - will monitoring assure that all home wells are O.K.?
  28. Current atrazine products contain requirements that are intended to prevent contamination of residential wells. Based on the limited available well monitoring data only 8 of 1505 wells sample had levels of atrazine that exceeded the level of concern. In each of those 8 wells additional samples were taken and found that levels no longer exceeded the level of concern. While the Agency does not believe that there is a risk of concern, in general, for rural wells it believes that a more intensive monitoring study is needed to confirm this conclusion. This study will be required as part of the IRED and will be designed specifically to determine if rural wells are at risk. In the event that this study leads the Agency to believe that there are risks of concern in rural wells, the Agency will require additional, appropriate mitigation measures.

  29. Recent studies and journals have raised new concerns regarding the potential effects of atrazine on frogs. Does the IRED address potential amphibian (frog) risk?
  30. EPA is in the process of evaluating data relating to potential effects of atrazine on amphibians from researchers representing eight universities. EPA is considering a number of additional new studies on potential amphibian risk. Where possible, raw data from these studies are being analyzed and study methods are being documented in order to perform our own, independent quality review of the studies. Additional information is expected to be submitted in the coming months, and the Consent Decree obligates EPA to review data relevant to these issues that is submitted before February 28, 2003 for an amendment to the IRED to be issued no later than January 31, 2003. OPP is planning to summarize all these studies in preparation for a FIFRA Science Advisory Panel (SAP) meeting where the potential effects of atrazine on amphibians will be discussed, and EPA will seek SAP guidance on the Agency’s assessment of these data and on other scientific issues concerning atrazine. The Agency’s amended IRED will incorporate the results of the SAP consultation on these issues.

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