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recombinant interleukin-1-alpha A recombinant agent which is chemically identical to or similar to the endogenous protein cytokine interleukin-1 (IL-1). The IL-1 precursor is produced by monocytes, activated macrophages, and other cell types; mature IL-1 is generated by proteolytic cleavage by proteases such as IL-1-beta converting enzyme (ICE). This agent enhances T cell proliferation and B cell growth and differentiation and induces the expression of proinflammatory cytokines. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081006060922im_/http://www.nci.nih.gov/images/spacer.gif) | interleukin-1-alpha | | ![](https://webarchive.library.unt.edu/eot2008/20081006060922im_/http://www.nci.nih.gov/images/spacer.gif) |
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