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indium In 111 monoclonal antibody huPAM4 The humanized monoclonal antibody huPAM4, directed against the pancreatic cancer antigen MUC-1 and radiolabled with the gamma-emitting radioisotope indium I 111, with radioisotopic and antibody activities. Upon administration, indium In 111 monoclonal antibody huPAM4 may bind to MUC-1-positive tumor cells, allowing radioimmunolocalization with gamma scintigraphy. Overexpressed by many tumor cell types, MUC-1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081006044914im_/http://www.nci.nih.gov/images/spacer.gif) | 111 In- labeled humanized PAM4 IgG | | ![](https://webarchive.library.unt.edu/eot2008/20081006044914im_/http://www.nci.nih.gov/images/spacer.gif) |
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