[Federal Register: December 30, 1999 (Volume 64, Number 250)]
[Notices]               
[Page 73563-73564]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr30de99-110]                         

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health and Human Services

 
National Heart, Lung, and Blood Institute; Proposed Collection; 
Comment Request The Multi-Ethnic Study of Atherosclerosis

Summary

    In compliance with the requirement of Section 3506(c)(2)(A) of the 
Paperwork Reduction Act of 1995, for opportunity for public comment on 
proposed data collection projects, the National Heart, Lung, and Blood 
Institute (NHLBI), the National Institutes of Health (NIH) will publish 
periodic summaries of proposed projects to be submitted to the Office 
of Management and Budget (OMB) for review and approval.

Proposed Collection

    Title: The Multi-Ethnic Study of Atherosclerosis.
    Type of Information Request: New.
    Need and Use of Information Collection: MESA is a cohort study 
evaluating people aged 45-84 years and measures of subclinical disease 
cardiovascular disease (disease detected before it has produced signs 
and symptoms) that predict progression to clinically overt disease in a 
diverse population. The purpose is to develop population-based methods 
for identifying asymptomatic people at high risk of clinical events. 
The results of this study will allow application for future screening 
for identification of people at increased risk for cardiovascular 
disease and intervention studies for treatment of those at increased 
risk. This study will include a substantial proportion of previously 
understudied minority groups.
    Need and use of Information Collection; Frequency of Response; 
Affected Public and Type of Respondents: The annual reporting burden is 
as follows:
    Estimated number of Respondents: 16,514;
    Estimated Responses/Respondent: 3.88;
    Average Burden Hours/Response: 4.55; and
    Estimated Total Annual Burden Hours Requested: 25,070.
    There are no costs for respondents. Estimated annualized cost for 
information collection for information collection for a 10-year period 
(in thousands) is $6870. The estimated annualized start-up costs are 
$756, and the estimated annualized operating and maintenance costs are 
$6114.

Request for Comments

    Written comments and/or suggestions from the public and affected 
agencies are invited on one or more of the following points: (1) 
Whether the proposed collection of information will have practical 
utility; (2) The accuracy of the agency's estimate of burden of the 
proposed collection of information, including the validity of the 
methodology and assumptions used; (3) Ways to enhance the quality, 
utility, and clarity of the information to be collected; and (4) Ways 
to minimize the burden of collection of information on those who are to 
respond, including the use of appropriate automated, electronic, 
mechanical, or other technological collection techniques or other forms 
of information technology.

For Further Information

    To request more information on the proposed project or to obtain a 
copy of data collection plans and instruments, contact Dr. Robin 
Boineau, Epidemiology and Biometry Program, Division of Epidemiology 
and Clinical Applications, NHLBI, NIH, II Rockledge Centre, 6701 
Rockledge Drive, MSC # 7934, Bethesda, MD, 20892-7934, or call non-
toll-free number (301) 435-0707, or E-mail your request, including your 
address to: boineau@nih.gov.

[[Page 73564]]

Comments Due Date

    Comments regarding this information collection are best assured of 
having their full effect if received on or before February 28, 2000.


    Dated: December 22, 1999.
Peter Savage,
Acting Director, Division of Epidemiology and Clinical Applications.
[FR Doc. 99-33910 Filed 12-29-99; 8:45 am]
BILLING CODE 4140-01-M