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[Federal Register: May 3, 2002 (Volume 67, Number 86)]
[Notices]               
[Page 22412-22413]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr03my02-33]                         

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DEPARTMENT OF DEFENSE

Department of the Army

 
Availability for Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Application Concerning Asporogenic B. 
ANTHRACIS Expression System

AGENCY: Department of the Army, DOD.

ACTION: Notice.

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[[Page 22413]]

SUMMARY: In accordance with 37 CFR 404.6 and 404.7, announcement is 
made of the availability for licensing of U.S. Patent No. 6,316,006 
entitled ``Asporogenic B. ANTHRACIS Expression System'' issued November 
13, 2001. The United States Government as represented by the Secretary 
of the Army has rights in this invention.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, 
ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, 
Frederick, MD 21705-5012.

FOR FURTHER INFORMATION CONTACT: For patent issues, Ms. Elizabeth 
Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul 
Mele, Office of Research & Technology Assessment, (301) 619-6664, both 
at telefax (301) 619-5034.

SUPPLEMENTARY INFORMATION: This invention relates to a bacterial 
expression system for production of protective antigen (PA) against 
bacillus anthrasis. Recombinant asporogenic B. anthracits that are 
derived from <greek-D>Sterne-1(pPA102) and show inability to bind the 
dye when grown on Congo Red Agar can be screened and asporogenic 
strains isolated using methods of the invention. Organisms of the 
invention lacking spore-forming function may be killed by heat shock at 
temperatures as low as 
60  deg.C. for 60 minutes. Hence, contamination of the environment with 
viable spore-forming organisms is easily avoided and decontamination is 
easily accomplished.

Luz D. Ortiz,
Army Federal Register Liaison Officer.
[FR Doc. 02-11067 Filed 5-2-02; 8:45 am]
BILLING CODE 3710-08-M

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