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NCI Cancer Bulletin
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November 28, 2006 • Volume 3 / Number 46 E-Mail This Document  |  Download PDF  |  Bulletin Archive/Search  |  Subscribe


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Featured Article
Cancer Stem Cells Detected in Colon Tumors

Director's Update
All Ireland-NCI Consortium Rolls On

Cancer Research Highlights
Eye-Sparing Method Effective for Ocular Melanoma Diagnosis

Nanoparticles Successfully Deliver Drugs to Brain Tumors in Mice

Risks Identified for New Solid Cancer after Stem Cell Transplants

Study Suggests Survival Benefit for Tamoxifen-Anastrozole Combo

FDA Update
FDA Expands Use of Herceptin for Early-Stage Breast Cancer After Primary Therapy

Spotlight
Giving Cancer an Energy Blackout

Featured Clinical Trial
Zactima for Recurrent or Progressive Brain Tumors

Notes
NIH Grants Must Be Submitted Electronically

AMA to Hold Meetings at Smoke-Free Sites

DNA Sequencing Centers to Examine Cancer

CCR Grand Rounds

Funding Opportunities

Community Update
End-of-Life Training Program on the Web is a Big Success

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Notes

CCR Grand Rounds
December 5: Dr. J. Silvio Gutkind, Chief, Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, NIH. "Head and Neck Cancer and Signaling Networks: Novel Mechanism-Based Therapies."

December 12: Dr. Mark Cushman, Professor of Medicinal Chemistry, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University; and Dr. Yves Pommier, Chief, Laboratory of Molecular Pharmacology, CCR, NCI. "Synthesis and Evaluation of Indenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors: an NCI Intra- and Extra-mural Partnership."

CCR Grand Rounds are held 8:30 to 9:30 a.m. at the NIH campus in Bethesda, Md., in the Clinical Center's Lipsett Amphitheater.

NIH Grants Must Be Submitted Electronically
For the February 5, 2007, R01 receipt date and beyond, NIH will require electronic application submission for all R01 applications. This change will involve the simultaneous shift from the long-used PHS 398 application form to a transagency Standard Form 424 Research and Related Application Form. For more information on electronic submission of applications, go to http://era.nih.gov/ElectronicReceipt/.

Investigators should work with their central grants offices to learn how their institutions are handling the changes. Training sessions will be held on December 5 from 9:00 a.m.-12:00 p.m. and from 1:00-4:00 p.m. in the Natcher Conference Center on the NIH campus. The sessions will be webcast at http://era.nih.gov/training/esub_120506/ and will be archived for later viewing at http://videocast.nih.gov/default.asp. Additional training resources are available at http://era.nih.gov/ElectronicReceipt/training.htm.

AMA to Hold Meetings at Smoke-Free Sites
At its semiannual policy making meeting on November 13, the American Medical Association (AMA) adopted a policy that calls for all AMA meetings and conferences to be held in communities and states that have enacted comprehensive legislation requiring smoke-free worksites and public places, including restaurants and bars. The AMA also called on other medical organizations to adopt similar policies.

Earlier this year, NCI adopted a smoke-free meeting site policy, which will take effect on January 1, 2007, requiring that all meetings and conferences organized or primarily sponsored by NCI be held in a state, county, city, or town that has adopted a comprehensive smoke-free policy.

DNA Sequencing Centers to Examine Cancer
On November 20, the National Human Genome Research Institute (NHGRI) announced the selection of three large-scale genetic sequencing centers, strengthening efforts to use the power of DNA sequencing to unlock the genomic secrets of human diseases. All three sequencing centers will devote a significant part of their efforts to The Cancer Genome Atlas (TCGA) Pilot Project, a joint initiative of NCI and NHGRI, which is testing the feasibility of a large-scale, systematic approach to identify important genomic changes involved in cancer. The three centers are the Broad Institute of the Massachusetts Institute of Technology and Harvard University; Washington University Genome Sequencing Center, Washington University School of Medicine; and the Human Genome Sequencing Center, Baylor College of Medicine.

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