Blood Stem Cell Transplants - National Cancer Institute

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National Cancer Institute
U.S. National Institutes of Health | www.cancer.gov

Understanding Cancer Series: Blood Stem Cell Transplants

In English

Posted: 09/01/2006 Reviewed: 09/01/2006

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Blood Stem Cell Transplants

Slide Number and Title

Stem Cells
Blood Stem Cells
From Bone Marrow to the Bloodstream
Blood Stem Cell Transplants: When?
Stem Cells from Self to the Rescue
Stem Cells from Donor to the Rescue
Not Just Any Blood Stem Cells Will Do
Host vs. Graft/Graft vs. Host
Tissue Typing Matches Donors to Patients
Many Names for the "Self" Antigens
Haplotypes: Passing on Genes for "Self" Antigens
6 Major Genes: 10,000 Antigens
Three Most Important Antigens
A "Clinical Match"
Some Haplotypes Occur More Often

Sometimes a 3-Antigen Match Is Necessary
A Delicate Balance: Graft vs. Tumor/Graft vs. Host
Success in Matching Varies With Population
Preparing Patients for Myeloablative Allogeneic Transplants
Preparing Patients for Reduced-Intensity Allogeneic Transplants
Preparing Donors for Allogeneic Transplants
Apheresis: Harvesting Stem Cells From Peripheral Blood
Preparing Patients for Autologous/Syngeneic Transplants
Cord Blood as a Source of Stem Cells
Placental and Cord-Blood Stem Cell Transplants
Using More Than One Cord-Blood Donor
Placental and Cord-Blood Transplants: Pros and Cons
New Development: Stockpiling
When a Blood Stem Cell Transplant Works
National Marrow Donor Program Helps Many

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