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prochlorperazine A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym: | | Compazine | | | Abbreviation: | | PCPZ | | | Code names: | | RP 6140 SKF-4657 | | | Chemical structure name: | | 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine | | |
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