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penicillamine A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | Depamine D-Mercaptovaline D-Penicillamine | | | US brand names: | | Cuprenil Cuprimine Depen Perdolat Sufortan | | | Foreign brand names: | | Atamir Cupripen Distamine Kelatin Mercaptyl Metalcaptase Pendramine Trolovol | | | Chemical structure names: | | - 3-Mercapto-D-valine
- Alpha-amino-beta-methyl-beta-mercaptobutyric Acid
- Beta,Beta-dimethylcysteine
- Beta-thiovaline
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