 |
|
genistein
A soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | CI 75610
Genestein
genisteol
genisterin
prunetol
sophoricol | | | | Chemical structure names: | | - 4',5,7-Trihydroxyisoflavone
- 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
| | |
|
|
