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dimethylxanthenone acetic acid A fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Dimethylxanthenone acetic acid induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti-tumor activity of tumor-associated macrophages. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | Dimethyloxoxanthene Acetic Acid | | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | 5,6-MexXAA DMXAA | | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | Code names: | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | AS1404 ASA404 | | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) | 5,6-Dimethylxanthenone-4-Acetic Acid | | ![](https://webarchive.library.unt.edu/eot2008/20081006041639im_/http://www.nci.nih.gov/images/spacer.gif) |
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