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lymphokine-activated killer cells Killer cell lymphocytes activated in the presence of interleukin-2 (IL-2). Lymphokine-activated killer cells (LAKs) are cytotoxic effector cells with an exceptionally wide target cell spectrum including normal and malignant cells of different origins. LAK cells exhibit a profound heterogeneity with regard to phenotype surface marker expression; it remains to be determined if they represent a unique cell lineage. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | LAK cells Therapeutic Lymphokine-Activated Killer Cell | | | Abbreviation: | | LAK | | |
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