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Agricultural Research Service United States Department of Agriculture
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David E Wedge
Natural Products Utilization Research
Research Plant Pathologist

Phone: (662) 915-1137
Fax: (662) 915-1035
Room 2022
UNIVERSITY OF MISSISSIPPI
UNIVERSITY, MS, 38677-8048

Projects
DISCOVERY AND DEVELOPMENT OF NATURAL PRODUCTS FOR CONTROL OF PLANT DISEASES IN AGRICULTURE
Appropriated (D)
  Accession Number: 408607
DISCOVERY OF NATURAL PRODUCTS FOR CONTROL OF PLANT DISEASES
Nonfunded Cooperative Agreement (N)
  Accession Number: 412120

Publications
Chemical Composition and Antifungal Activity of Angelica sinensis Essential Oil Against Three Colletotrichum Species - (Peer Reviewed Journal)
Tabanca, N., Wedge, D.E., Wang, X., Demirci, B., Baser, K., Zhou, L., Cutler, S.J. 2008. Chemical Composition and Antifungal Activity of Angelica sinensis Essential Oil Against Three Colletotrichum Species. Natural Product Communications. 3(7):1073-1078.
Isolation and Identification of Antifungal Fatty Acids from the Basidiomycete Gomphus floccosus - (Peer Reviewed Journal)
Cantrell, C.L., Case, B.P., Mena, E., Kniffin, T.M., Duke, S.O., Wedge, D.E. 2008. Isolation and Identification of Antifungal Fatty Acids from the Basidiomycete Gomphus floccosus. Journal of Agricultural and Food Chemistry. 56:5062-5068.
Development of a Miniaturized 24-well Strawberry Leaf Disk Bioassay for Evaluating Natural Fungicides - (Peer Reviewed Journal)
Wang, X., Wedge, D.E., Tabanca, N., Johnson, R.D., Cutler, S.J., Pace, P., Smith, B.J., Zhou, L. 2008. Development of a Miniaturized 24-well Strawberry Leaf Disk Bioassay for Evaluating Natural Fungicides. Natural Product Communications. 3(7):1079-1084.
Evaluation of CAY-1, an Experimental, Natural Fungicide for Control of Strawberry Pathogens - (Peer Reviewed Journal) - (15-Mar-08)
Phytotoxic Eremophilanes from Ligularia macrophylla - (Peer Reviewed Journal)
Cantrell, C.L., Duke, S.O., Fronczek, F.R., Osbrink, W.L., Mamonov, L.K., Vassilyev, J.I., Wedge, D.E., Dayan, F.E. 2007. Phytotoxic Eremophilanes from Ligularia macrophylla. Journal of Agricultural and Food Chemistry. v. 55:10656-10663.
Natural Products for Pest Management - (Book/Chapter)
Duke, S.O., Rimando, A.M., Schrader, K., Cantrell, C.L., Meepagala, K.M., Wedge, D.E., Tabanca, N., Dayan, F.E. 2008. Natural Products for Pest Management in Selected Topics of Natural Products. R. Ikan, ed., World Sci. Publishing Co., Singapore, pp. 209-251.
Agricultural Application of Higher Plants for Their Antimicrobial Potentials in China - (Book/Chapter)
Zhou, L., Wedge, D.E. 2008. Agricultural Application of Higher Plants for Their Antimicrobial Potentials in China. In Crop Protection Research Advances, E.N. Burton and P.V. Williams, Eds., Nova Science Publishers, Hauppauge, NY. PP. 55-75.
Improved Microassays Used to Test Natural Product-Based and Conventional Fungicides on Plant Pathogenic Fungi - (Peer Reviewed Journal)
Abril, M., Curry, K.J., Smith, B.J., Wedge, D.E. 2008. Improved Microassays Used to Test Natural Product-Based and Conventional Fungicides on Plant Pathogenic Fungi. Plant Disease. 92(1):106-112.
Composition, Enantiomeric Distribution and Antimicrobial Activity of the Essential Oil of Tanacetum argenteum subsp. flabellifolium Essential Oil - (Peer Reviewed Journal)
Tabanca, N., Demirci, F., Demirci, B., Wedge, D.E., Can Baser, K. 2007. Composition, Enantiomeric Distribution and Antimicrobial Activity of the Essential Oil of Tanacetum argenteum subsp. flabellifolium Essential Oil. Journal of Pharmaceutical and Biomedical Analysis. 45:714-719.
Chemical Composition and Antifungal Activity of Arnica longifolia, Aster hesperius and Chrysothamnus nauseosus Essential Oils - (Peer Reviewed Journal)
Tabanca, N., Demirci, B., Crockett, S.L., Can Baser, K., Wedge, D.E. 2007. Chemical Composition and Antifungal Activity of Arnica longifolia, Aster hesperius and Chrysothamnus nauseosus Essential Oils. Journal of Agricultural and Food Chemistry. 55(21):8430-8435.
Flavan-3-ol-phenylpropanoid Conjugates from Anemopaegma arvense and Their Antioxident Activites - (Peer Reviewed Journal)
Tabanca, N., Pawar, R.S., Ferreira, D., Marais, J.J., Khan, S.I., Wedge, D.E., Khan, I.A. 2007. Flavan-3-ol-phenylpropanoid Conjugates from Anemopaegma arvense and Their Antioxident Activites. Planta Medica. 73:1107-1111.
In Vitro Assessment of Plant Essential Oils Inhibitory Against Phomopsis Longicolla, the Fungus That Causes Soybean Seed Decay - (Abstract)
Li, S., Zhang, S., Lui, Z., Tabanca, N., Wedge, D.E. 2007. In Vitro Assessment of Plant Essential Oils Inhibitory Against Phomopsis Longicolla, the Fungus That Causes Soybean Seed Decay. American Phytopathological Society Annual Meeting. 97:S64.
The Lysosome and HER3 (ErbB3) Selective Anticancer Agent Kahalalide F: Semisynthetic Modifications and Antifungal Lead-Exploration Studies - (Peer Reviewed Journal)
Shilabin, A., Kasanah, N., Wedge, D.E., Hamann, M.T. 2007. The Lysosome and HER3 (ErbB3) Selective Anticancer Agent Kahalalide F: Semisynthetic Modifications and Antifungal Lead-Exploration Studies. Journal of Medicinal Chemistry. 50:4340-4350.
Interactions of Synthetic Herbicides with Plant Disease and Microbial Herbicides - (Book/Chapter)
Duke, S.O., Wedge, D.E., Cerdeira, A.L., Matallo, M.B. 2007. Interactions of Synthetic Herbicides with Plant Disease and Microbial Herbicides. Book chapter. In Novel Biotechnologies for Biocontrol Agent Enhancement and Management, M. Vurro & J. Gressel, eds., Springer, The Netherlands. pp.277-296.
Herbicide Effects on Plant Disease - (Review Article)
Duke, S.O., Wedge, D.E., Cerdeira, A.L., Matallo, M.B. 2007. Herbicide Effects on Plant Disease. Pest Management Science. 18:36-40.
Recent Advances in the Chemistry and Biological Activities of the Pimpinella Species of Turkey - (Peer Reviewed Journal)
Can Baser, K., Tabanca, N., Kirimer, N., Bedir, E., Khan, I.A., Wedge, D.E. 2007. Recent Advances in the Chemistry and Biological Activities of the Pimpinella Species of Turkey. Journal of Pure and Applied Chemistry. V. 79(4):539-556.
Characterization of Volatile Constituents of Scaligeria tripartita and Studies on the Antifungal Activity Against Phytopathogenic Fungi - (Peer Reviewed Journal)
Tabanca, N., Demirci, B., Can Baser, K., Mincsovics, E., Khan, S.I., Jacob, M.R., Wedge, D.E. 2007. Characterization of Volatile Constituents of Scaligeria tripartita and Studies on the Antifungal Activity Against Phytopathogenic Fungi. Journal of Chromatography B. V. 850:221-229.
FUNGICIDE MANAGEMENT OF FRUIT ROT DISEASES OF STRAWBERRY IN LOUISIANA AND MISSISSIPPI - (Peer Reviewed Journal)
Wedge, D.E., Smith, B.J., Constantin, R.J., Quebedeaux, J.P. 2007. Fungicide management of fruit rot diseases of strawberry in louisiana and mississippi. Crop Protection Journal. 26:1449-1458
ALGICIDAL AND ANTIFUNGAL COMPOUNDS FROM THE ROOTS OF RUTA GRAVEOLENS AND SYNTHESIS OF THEIR ANALOGS - (Peer Reviewed Journal)
Meepagala, K.M., Schrader, K., Wedge, D.E., Duke, S.O. 2005. Algicidal and antifungal compounds from the roots of ruta graveolens and synthesis of their analogs. Phytochemistry. 66(22): 2689-2695.
Chemical Composition and Antifungal Activity of Salvia macrochlamys and Salvia recognita Essential Oils - (Peer Reviewed Journal)
Tabanca, N., Demirci, B., Can Baser, K., Aytac, Z., Ekici, M., Khan, S.I., Jacob, M.R., Wedge, D.E. 2006. Chemical Composition and Antifungal Activity of Salvia macrochlamys and Salvia recognita Essential Oils. Journal of Agricultural and Food Chemistry. 54:6593-6597.
GAS CHROMATOGRAPHIC-MASS SPECTROMETRIC ANALYSIS OF ESSENTIAL OILS FROM PIMPINELLA SPECIES GATHERED FROM CENTRAL AND NORTHERN TURKEY - (Peer Reviewed Journal)
Tabanca, N., Demirci, B., Ozek, T., Kirimer, N., Can Baser, K., Bedir, E., Khan, I.A., Wedge, D.E. 2006. Gas chromatographic-mass spectrometric analysis of essential oils from pimpinella species gathered from central and northern turkey. Journal of Chromatography A. 1117: 194-205.
CHARACTERIZATION OF VOLATILE CONSTITUENTS OF HAPLOPAPPUS GREENEI AND STUDIES ON THE ANTIFUNGAL ACTIVITY AGAINST PHYTOPATHOGENS - (Peer Reviewed Journal)
Demirci, B., Can Baser, K., Tabanca, N., Wedge, D.E. 2006. Characterization of volatile constituents of haplopappus greenei and studies on the antifungal activity against phytopathogens. Journal of Agricultural and Food Chemistry. 54:3146-3150.
Efficacy of Two Novel Fungicides for Control of Strawberry Anthracnose - (Abstract)
Abril, M., Curry, K.J., Smith, B.J., Wedge, D.E. 2006. Efficacy of Two Novel Fungicides for Control of Strawberry Anthracnose. Phytopathology. 95:S2.
ANTIFUNGAL ACTIVITY OF THIOPHENES FROM ECHINOPS RITRO - (Peer Reviewed Journal)
Fokialakis, N., Cantrell, C.L., Duke, S.O., Skaltsounis, A.L., Wedge, D.E. 2006. Antifungal activity of thiophenes from echinops ritro. Journal of Agricultural and Food Chemistry. 54: 1651-1655.
GAS CHROMATOGRAPHIC-MASS SPECTROMETRIC ANALYSIS OF ESSENTIAL OILS FROM PIMPINELLA AUREA, PIMPINELLA CORYMBOSA, PIMPINELLA PEREGRINA AND PIMPINELLA PUBERULA GATHERED FROM EASTERN AND SOUTHERN TURKEY - (Peer Reviewed Journal)
Tabanca, N., Demirci, B., Kirimer, N., Can Baser, K., Bedir, E., Khan, I.A., Wedge, D.E. 2005. Gas chromatographic-mass spectrometric analysis of essential oils from pimpinella aurea, pimpinella corymbosa, pimpinella peregrina and pimpinella puberula gathered from eastern and southern turkey. Journal of Chromatography A. 1097:192-198.
ISOLATION AND IDENTIFICATION OF ANTIFUNGAL AND ANTIALGAL ALKALOIDS FROM HAPLOPHYLLUM SIEVERSII - (Peer Reviewed Journal)
Cantrell, C.L., Schrader, K., Mamonov, L.K., Sitpaeva, G.T., Kustova, T.S., Dunbar, C., Wedge, D.E. 2005. Isolation and identification of antifungal and antialgal alkaloids from haplophyllum sieversii. Journal of Agricultural and Food Chemistry. 53(20):7741-7748.
SENSITIVITY OF SELECTED PLANT PATHOGENIC FUNGI TO SAMPANGINE AND ITS ANALOGS - (Abstract)
Abril, M., Curry, K.J., Wedge, D.E., Smith, B.J. 2005. Sensitivity of selected plant pathogenic fungi to sampangine and its analogs. Phytopathology vol.95, no.6:S2.
DISCOVERY AND EVALUATION OF NATURAL PRODUCT-BASED FUNGICIDES FOR DISEASE CONTROL OF SMALL FRUITS - (Book/Chapter)
Wedge, D.E., Smith, B.J. Inderjit, Mukerji, K.G., editors. Springer, The Netherlands. Discovery and evaluation of natural product-based fungicides for disease control of small fruits. 2006. p. 1-15.
INSECTICIDAL ACTIVITY OF 23 ESSENTIAL OILS AND THEIR MAJOR COMPOUNDS AGAINST ADULT LIPAPHIS PSEUDOBRASSICAE (DAVIS) (APHIDIDAE: HOMOPTERA) - (Peer Reviewed Journal)
Sampson, B.J., Tabanca, N., Kirimer, N., Demirci, B., Can Baser, K.H., Khan, I.A., Spiers, J.M., Wedge, D.E. 2005. Insecticidal activity of 23 essential oils and their major compounds against adult lipaphis pseudobrassicae (davis) (aphididae: homoptera). Pest Management Science. 61: 1122-1128.
PLANT-DERIVED ANTIFUNGAL COMPOUNDS AND CURRENTLY EMPLOYED MICROBIAL-BASED AGRICULTURAL FUNGICIDES - (Peer Reviewed Journal)
De Lucca II, A.J., Cleveland, T.E., Wedge, D.E. 2005. Plant-derived antifungal proteins and peptides. Canadian Journal of Microbiology. 51:1001-1014.
PHYTOTOXIC AND ANTIFUNGAL COMPOUNDS FROM TWO APIACEAE SPECIES, LOMATIUM CALIFORNICUM AND LIGUSTICUM HULTENII, RICH SOURCES OF Z-LIGUSTILIDE AND APIOL, RESPECTIVELY. - (Peer Reviewed Journal)
Meepagala, K.M., Sturtz, G., Wedge, D.E., Schrader, K., Duke, S.O. 2005. Phytotoxic and antifungal compounds from two apiaceae species, lomatium californicum and ligusticum hultenii, rich sources of z-ligustilide and apiol, respectively.. Journal of Chemical Ecology. 31:1567-1578.
FINDING FUNGICIDES FROM NATURAL SOURCES - (Book/Chapter)
Wedge, D.E., Duke, S.O. Finding fungicides from natural sources. Rimando, A.M., Duke, S.O., editors. American Chemical Society, Washington, DC. Natural Products for Pest Management. 2006. pp. 152-167.
BIOTRANSFORMATION STUDIES OF THE MANZAMINE ALKALOIDS - (Peer Reviewed Journal)
Kasanah, N., Rao, K., Yousaf, M., Wedge, D.E., Hill, R.T., Hamann, M.T. 2004. Biotransformation studies of the manzamine alkaloids. Marine Biotechnology. 6:268-272.
BIOACTIVE CONSTITUENTS FROM TURKISH PIMPINELLA SPECIES - (Peer Reviewed Journal)
Tabanca, N., Bedir, E., Ferreira, D., Slade, D., Wedge, D.E., Jacob, M.R., Khan, S.I., Kirimer, N., Can Baser, K., Khan, I.A. 2005. Bioactive constituents from turkish pimpinella species. Chemistry and Biodiversity. 2:221-232.
FUNGICIDE MANAGEMENT OF FRUIT DISEASES OF STRAWBERRY IN LOUISIANA AND MISSISSIPPI - (Abstract)
Smith, B.J., Constantin, R.J., Quebedeaux, J.P., Wedge, D.E. 2004. Fungicide management of fruit diseases of strawberry in Louisiana and Mississippi. Phytopathology. 94:S169
PAW PAW EXTRACT AS A BOTANICAL INSECTICIDE, 2002 - (Peer Reviewed Journal)
Sampson, B.J., J.L. McLaughlin, D.E. Wedge. 2003. PawPaw Extract as a Botanical Insecticide, 2002. Arthropod Management Tests, vol.28,p.L5
ANTIFUNGAL CLERODANE DITERPENES FROM MACARANGA MONANDRA (L) MUELL. ET ARG. (EUPHORBIACEAE) - (Peer Reviewed Journal)
SALAH, M., BEDIR, E., TOYANG, N., KHAN, I., HARRIES, M.D., WEDGE, D.E. 2003.ANTIFUNGAL CLERODANE DITERPENES FROM MACARANGA MONANDRA (L) MUELL. ET ARG. (EUPHORBIACEAE). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 51:7607-7610.
COMPARATIVE EFFECTS OF EIGHT VARIETIES OF BLACKBERRY ON MUTAGENESIS - (Peer Reviewed Journal)
Tate, P., Kuzmar, A., Smith, S.W., Wedge, D.E., Larcom, L.L. 2003. Comparative effects of eight varieties of blackberry on mutagenesis. Nutrition Research. 23:971-979.
ACTIVITY OF QUINONES ON COLLETOTRICHUM SPECIES - (Peer Reviewed Journal)
MEAZZA, G., DAYAN, F.E., WEDGE, D.E. 2003. Acativity of quinones on colletotrichum species. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 51:3824-3828.
DEVELOPMENT OF STANDARDIZED TECHNIQUES FOR SCREENING NATURAL PRODUCT FUNGICIDES - (Abstract)
Curry, K.J., Wedge, D.E., Smith, B.J. 2004. Development of standardized techniques for screening natural product fungicides. Phytopathology. 94:S167
NATURAL FUNGICIDES FROM RUTA GRAVEOLENS L. LEAVES, INCLUDING A NEW QUINOLONE ALKALOID - (Peer Reviewed Journal)
OLIVA, A., MEEPAGALA, K.M., WEDGE, D.E., HARRIES, M.D., HALE, A.L., ALIOTTA, G., DUKE, S.O. 2003. NATURAL FUNGICIDES FROM RUTA GRAVEOLENS L. LEAVES, INCLUDING A NEW QUINOLONE ALKALOID. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 51(4):890-896.
THE BIOCATALYTIC CONVERSION OF 8-HYDROXYMANZAMINE A TO MANZAMINE A - (Peer Reviewed Journal)
Kasanah, N., Rao, K.V., Yousaf, M., Wedge, D.E., Hamann, M.T. 2003. The biocatalytic conversion of 8-hydroxymanzamine A to manzamine A using Fusarium solani. Tetrahedron Letters. 44(6):1291-1293.
AGROCHEMICAL DISCOVERY: FINDING NEW FUNGICIDES FROM NATURAL PRODUCTS - (Proceedings/Symposium)
Wedge, D.E. 2005. Agrochemical discovery: finding new fungicides from natural products. Acta Horticulture Proceedings. 3:109-113.
PRELIMINARY RESULTS OF STRAWBERRY FUNGICIDE STUDY - (Experiment Station)
Constantin, R.J., Quebedeaux, J.P., Smith, B.J., Wedge, D.E. 2003. Preliminary results of strawberry fungicide study. Citrus, Fruit and Nut Research Summary 2001-2002. Louisiana State University Agricultural Center Strawberry Research Summary. 147:88-93.
ARS RESEARCH ON NATURAL PRODUCTS FOR PEST MANAGEMENT - (Review Article)
DUKE, S.O., BAERSON, S.R., DAYAN, F.E., RIMANDO, A.M., SCHEFFLER, B.E., TELLEZ, M.R., WEDGE, D.E., AKEY, D.H., ARTHUR, F.H., DE LUCCA II, A.J. ARS RESEARCH ON NATURAL PRODUCTS FOR PEST MANAGEMENT. PEST MANAGEMENT SCIENCE. 2003. V.59:708-717.

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Last Modified: 10/03/2008
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