DOE Human Genome Program Contractor-Grantee Workshop VIII
February 27-March 2, 2000  Santa Fe, NM

135. Getting the Word Out on the Human Genome Project: A Course for Physicians

Sara L. Tobin¹ and Ann Boughton²

¹Program for Genomics, Ethics, and Society, Stanford University Center for Biomedical Ethics, Palo Alto, CA 94304 and ²Thumbnail Graphics

tobinsl@leland.stanford.edu

Progressive identification of new genes and implications for medical treatment of genetic diseases appear almost daily in the scientific and medical literature, as well as in public media reports. However, most physicians completed their medical training prior to the application of recombinant DNA technology to medical diagnosis and treatment. Such individuals do not understand the promise or the limitations of the current explosion in knowledge of the human genome. This project is designed to fill two important functions: first, to provide physicians with a solid foundation in molecular medical genetics, including the impact, implications, and potential of this field for the treatment of human disease; second, to utilize physicians as informed community resources who can educate both their patients and community groups about the new genetics.

We are completing the development of a flexible, user-friendly, interactive multimedia CD-ROM designed for continuing education of physicians in applications of molecular medical genetics. Following the completion and evaluation of a prototype, we have focused on content creation and upgrades to the multimedia tool. The courseware will provide training in four areas: (1) Genetics, including DNA as a molecular blueprint and patterns of inheritance; (2) Recombinant techniques, stressing cloning and analytical tools and techniques applied to medical case studies; (3) Current and future clinical applications, encompassing technical advances and disease diagnosis and prognosis; and (4) Societal implications, focusing on issues such as confidentiality, discrimination, and impact on the family.

The multimedia format permits the use of animation, video, and audio, in addition to graphic illustrations and photographs. Novel features are utilized to tailor the CD to the needs of the user, and continuing medical education credits will be available through Stanford. The CD will function as a "hybrid" product, capable of seamless interaction with Internet resources and updated content.