| Patients without a colostomy |
None |
Increase of <4 stools/day over pretreatment |
Increase of 4–6 stools/day or nocturnal stools |
Increase of ≥7 stools/day |
>10 stools/day |
| None |
None |
Moderate cramping, not interfering with normal activity |
Severe cramping and incontinence, interfering with daily activities |
Grossly bloody diarrhea and need for parenteral support |
| Patients with a colostomy |
None |
Mild increase in loose, watery colostomy output compared with pretreatment |
Moderate increase in loose, watery colostomy output compared with pretreatment, but not interfering with normal activity |
Severe increase in loose, watery colostomy output compared with pretreatment, interfering with normal activity |
Physiological consequences requiring intensive care; hemodynamic collapse |
| For patients undergoing bone marrow transplant (BMT) |
None |
>500 mL to ≤1,000 mL of diarrhea/day |
>1,000 mL to ≤1,500 mL of diarrhea/day |
>1,500 mL of diarrhea/day |
Severe abdominal pain with or without ileus |
| For children undergoing BMT |
None |
>5 mL/kg to ≤10 mL/kg of diarrhea/day |
>10 mL/kg to ≤15 mL/kg of diarrhea/day |
>15 mL/kg of diarrhea/day |
Severe abdominal pain with or without ileus |
