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Gene Info

Gene Information For:Hs. CDK4, Cyclin-dependent kinase 4
Sequence ID:NM_000075

Database Links

UniGeneEntrez GeneCGWBOMIMDTPSNPViewerAssembliesCancer AberrationsSNP500CancerRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 56430876 - 56432414

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2961345Full LengthBC005864cyclin-dependent kinase 4
3531300Full LengthBC010153cyclin-dependent kinase 4
3532812Full LengthBC003644cyclin-dependent kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000066  

Protein Infomation

RefSeq

mRNAProteinSwissProtEnzymePfam Motifs
NM_000075 NP_000066 Q6FG61
P11802
EC 2.7.11.22 Pkinase
NM_005981 NP_005972 Q53X76
Q12999
  Tetraspannin
NM_138396 NP_612405 Q86YJ5   zf-C3HC4

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U01160 AAA17782 Q53X76
Q12999
 
M14505 AAA35673 Q6FG61
P11802
EC 2.7.11.22
U79269 AAB50213 Q6LC83  
BC003644 AAH03644 Q6FG61
P11802
EC 2.7.11.22
BC005864 AAH05864 Q6FG61
P11802
EC 2.7.11.22
BC009489 AAH09489 Q86YJ5  
BC010153 AAH10153 Q6FG61
P11802
EC 2.7.11.22
BC010377 AAH10377 Q53X76
Q12999
 
BC015669 AAH15669 Q96BE9  
BC036455 AAH36455 Q86YJ5  
BC050397 AAH50397 Q86YJ5  
DQ892877 ABM83803    
DQ893137 ABM84063    
DQ896127 ABM87126    
DQ896420 ABM87419    
AK093897 BAC04247 Q8N9T1  
AB209699 BAD92936 Q59EW2  
AK313701 BAG36447 B2R9A0  
AK315765 BAG38117 Q53X76  
AK294128 BAG57458 B4DFJ7  
AK297901 BAG60221 B4DNF9  
Z48970 CAA88834 P11802 EC 2.7.11.22
CR407647 CAG28575 Q53X76
Q12999
 
CR407668 CAG28596 Q6FG61
P11802
EC 2.7.11.22
CR542247 CAG47043 Q6FG61
P11802
EC 2.7.11.22

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CDK4 NP_000066 M.musculus Cdk4 12567 Gene Info NP_034000 95
R.norvegicus Cdk4 94201   NP_446045 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta

Kegg Pathways
Pathway information courtesy of Kegg


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