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Allergy and Asthma Newsletter
February 4, 2008


In This Issue
• Allergy Shots Are Effective Treatment for Symptoms
• Secondhand Smoke Worsens Lung Function in Cystic Fibrosis Patients
• Cold Meds Send 7,000 U.S. Kids to ER Each Year
 

Allergy Shots Are Effective Treatment for Symptoms


SATURDAY, Jan. 26 (HealthDay News) -- If you have allergic asthma, rhinitis, conjunctivitis or stinging insect allergies, you may be a good candidate for allergy shots, also known as immunotherapy.

That's the recommendation of the American Academy of Allergy, Asthma & Immunology.

"Immunotherapy is a form of treatment that aims to decrease sensitivity to substances called allergens," Dr. Linda Cox, chair of the AAAAI's Immunotherapy and Allergy Diagnostics Committee, said in a prepared statement.

"Allergens, like pollen, mold or animal dander, are substances that trigger allergy symptoms when an allergic person is exposed to them. Patients who receive immunotherapy are injected with increasing amounts of an allergen until the target therapeutic dose is reached, in an effort to build resistance to specific allergens," Cox explained.

She said relief of allergy symptoms can last long after completion of treatment and that immunotherapy helps prevent the development of new allergies and may prevent the progression of allergic rhinitis to asthma.

Immunotherapy involves injections of gradually increasing doses of a particular allergen. Your body responds by developing immunity or tolerance to the allergen, resulting in decreased symptoms when you're exposed to the allergen.

While immunotherapy is recommended for people with allergic asthma, rhinitis, conjunctivitis and stinging insect allergies, it's not recommended for those with food allergies, the AAAAI said. The best option for people with food allergies is to avoid foods that pose a danger.

The AAAAI says people should see a doctor about immunotherapy if they:

  • Have a clear relationship between asthma, rhinitis, conjunctivitis, and exposure to an allergen,
  • Have a poor response to allergy medication or avoidance measures,
  • Have a long duration of allergy symptoms (most of the year),
  • Are a child with rhinitis, because of the potential role of allergen immunotherapy in the progression of allergic disease.

More information

To learn more, visit the American Academy of Allergy, Asthma & Immunology  External Links Disclaimer Logo.


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Secondhand Smoke Worsens Lung Function in Cystic Fibrosis Patients


TUESDAY, Jan. 29 (HealthDay News) -- Exposure to secondhand smoke worsens lung function in people with cystic fibrosis (CF), especially those with certain genetic variations, say U.S. researchers.

"Despite public health warnings, including a recent U.S. surgeon general's report stating that there is no risk-free level of secondhand smoke exposure, substantial numbers of individuals with CF are exposed to secondhand smoke. Unfortunately, published studies have been inconsistent in associating poorer clinical outcomes in patients with CF with secondhand smoke exposure," the Johns Hopkins University researchers wrote.

The researchers looked at several areas involving secondhand smoke and CF, a fatal disorder that affects more than 30,000 people in the United States. They analyzed data on hundreds of CF patients, and found that secondhand smoke exposure was associated with decreases in all measures of lung function studied. Socioeconomic status did not worsen the relationship between secondhand smoke and reduced lung function.

The researchers also found that certain mutations in the CF-causing gene (CFTR) determine the degree of effect that secondhand smoke has on lung function in CF patients.

The study is published in the Jan. 30 issue of the Journal of the American Medical Association.

"CF may be a good model for uncovering gene-environment interactions that are detrimental to lung function. This study also raises the specter that healthy children bearing certain genetic variants may be at much higher risk for worse outcomes as a result of secondhand smoke exposure," the study authors wrote.

"Demonstration that genetically defined subsets of patients with CF exposed to secondhand smoke in the home have a substantial lifetime reduction in lung function provides potent justification for eradication of cigarette smoke exposure for all individuals with this life-limiting disorder," they concluded.

More information

The March of Dimes has more about cystic fibrosis  External Links Disclaimer Logo.


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Cold Meds Send 7,000 U.S. Kids to ER Each Year


MONDAY, Jan. 28 (HealthDay News) -- Some 7,000 American children under the age of 11 are treated each year in hospital emergency rooms because of problems with cough and cold medications, the U.S. Centers for Disease Control and Prevention reported Monday.

"In the majority of cases, these ER visits are due to unsupervised ingestion," said study lead author Dr. Melissa K. Schaefer, of the CDC's Division of Healthcare Quality Promotion.

The 7,000 cases are just under 6 percent of emergency room visits from all other medications combined, Schaefer said. "Any medication in the hand of a 3-year-old is a problem," she said. "It is important to focus on this, because these are all preventable emergency department visits."

In the study, released early by the journal Pediatrics and published online Monday, researchers used data from the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project to analyze emergency department visits due to cough and cold medications in 2004 and 2005.

They found that children aged 2 to 5 years old made up 64 percent of all emergency department visits for adverse reactions to cough and cold medications. Among these youngest children, 80 percent of the problems arose from unsupervised ingestions. Overall, roughly two-thirds of all the children studied wound up in the ER because of unsupervised ingestion.

Most of the children, 93 percent, did not need to be admitted to the hospital. But, one-fourth needed additional treatment to get the medicine out of their system, the researchers reported.

The over-the-counter cough and cold products the researchers reviewed in the study included decongestants, expectorants and antitussives. The products may also have included antihistamines. Labels could include the terms "nasal decongestants," "cough suppressants," "expectorants" and "antihistamines."

Earlier this month, the U.S. Food and Drug Administration issued a public health advisory stating that over-the-counter cough and cold medicines should not be given to infants and children under the age of 2. The safety of these products for children ages 2 to 11 is currently being reviewed by the FDA.

Right before the FDA held an advisory committee meeting in October that ultimately led to a recommendation for a ban on cold medicines for children under the age of 2, the makers of dozens of cough and cold remedies targeted to infants voluntarily recalled some of these products. Overall, there are approximately 800 popular cough and cold medicines sold in the United States. Experts estimate that Americans spend about $2 billion annually on these types of medications.

The CDC cautioned that parents also should not use products intended for older children to treat young children, and should keep all cough and cold medications out of the reach of children. In addition, parents should throw out products they may have that were sold to be used for infants and toddlers aged 2 and younger.

The CDC's Schaefer thinks that parents need to be educated about the dangers of letting children get their hands on these medications. In addition, Schaefer's team recommends that the makers of these drugs redesign their packaging to make it impossible for children to open these drugs.

"Parents should not substitute medications meant for older children for children under 2," Schaefer said. "In addition, parents should not tell children these medications are candy, and they should not take their own medications in front of their children."

The head of the drug industry group the Consumer Healthcare Products Association said the new study underscores the safety of these products when used properly.

"This CDC review puts the overall discussion of pediatric cough and cold remedies into perspective by focusing on concrete data that address the real issue," Linda A. Suydam, president of the Consumer Healthcare Products Association, said in a statement. "These medicines are safe when used as directed, and this government review underscores the importance of educating consumers -- especially those with small children -- on the safe use and safekeeping of medicine."

One expert sees no reason for parents to give children these medicines in the first place.

"There is no evidence that these medicines work to make you better faster," said Dr. Karen Sheehan, medical director of injury prevention and research at Children's Memorial Hospital in Chicago, and medical director of the Injury Free Coalition for Kids. "There is no reason to make them available, because we know bad things can happen to kids."

The way to treat a child with a cold is to make the child comfortable, give Tylenol for fever, lots of liquids and use a humidifier, Sheehan said. "The kids have the ability [to get better] on their own," she said.

More information

For more on coughs and colds, visit the American Lung Association  External Links Disclaimer Logo.


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