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17-ketosteroids

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Contents of this page:

Illustrations

Urine sample
Urine sample

Definition    Return to top

17-ketosteroids are substances that form when the body breaks down male steroid sex hormones called androgens and other hormones released by adrenal cortex. This article discusses the laboratory test used to measure the amount of 17-ketosteroids in a urine sample.

How the Test is Performed    Return to top

A 24-hour urine sample is needed.

For an infant, thoroughly wash the area around the urethra. Open a urine collection bag (a plastic bag with an adhesive paper on one end), and place it on the infant. For males, place the entire penis in the bag and attach the adhesive to the skin. For females, place the bag over the labia. Diaper as usual over the secured bag.

This procedure may take a couple of attempts -- lively infants can move the bag, causing the urine to be absorbed by the diaper. Check the infant frequently and change the bag after the infant has urinated into it. Drain the urine from the bag into the container provided by your health care provider.

Deliver it to the laboratory or your health care provider as soon as possible upon completion.

How to Prepare for the Test    Return to top

Your health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test.

Drugs that can increase 17-ketosteroids measurements include

Drugs that can decrease 17-ketosteroids measurements include:

How the Test Will Feel    Return to top

The test involves only normal urination, and there is no discomfort.

Why the Test is Performed    Return to top

Your doctor may order this test if you have signs of a disorder associated with abnormal levels of androgens.

Normal Results    Return to top

Normal values are as follows:

Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What Abnormal Results Mean    Return to top

Increased levels of 17-ketosteroids may indicate:

Decreased levels of 17-ketosteroids may indicate:

Risks    Return to top

There are no risks.

Update Date: 10/24/2007

Updated by: Robert Hurd, MD, Professor of Endocrinology, Department of Biology, Xavier University, Cincinnati, OH, and physician in the Primary Care Clinic, Cincinnati Veterans Administration Medical Center, Cincinnati, Ohio. Review provided by VeriMed Healthcare Network.

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