Dr. Marce Lorenzen Research Molecular Biologist Biological Research Unit Grain Marketing & Production Research Center 1515 College Ave. Manhattan, KS 66502 Voice: (785) 776-2712 Fax: (785) 537-5584 marce.lorenzen@ars.usda.gov ars.usda.gov/npa/gmprc/bru/lorenzen

Research Interests

Marcé Lorenzen is a Postdoctoral Research Molecular Biologist with the USDA-ARS Grain Marketing and Production Research Center located in Manhattan Kansas. She received her Ph.D. in Molecular Genetics from Kansas State University in 2000 and a B.S. in Zoology from the University of Rhode Island in 1994. Prior to joining the GMPRC team in July 2004, she was a Postdoctoral Research Fellow at the Kansas State University Division of Biology where she developed an insertional mutagenesis system for Tribolium. Her interests are Tribolium genetics and genomics. Her current research focus includes: cloning and characterizing neurotransmitter symporters, elucidating molecular mechanisms that underlie the maternally acting selfish gene Medea, genome-wide insertional mutagenesis and data mining of the Tribolium genome as sequence data becomes available from the Human Genome Sequencing Center, Baylor College of Medicine.

Selected Publications

To list all publications and request reprints for which no PDF file is available, click here.
PDF	Lorenzen, M.D., A. Gnirke, J. Margolis, J. Garnes, M. Campbell, J.J. Stuart, R. Aggarwal, S. Richards, Y. Park, and R.W. Beeman. 2008. The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon. Proc. Natl. Acad. Sci. USA 105: 10085-10089.
PDF	Park, Y., J. Aikins, L.J. Wang, R.W. Beeman, B. Oppert, J.C. Lord, S.J. Brown, M.D. Lorenzen, S. Richards, G.M. Weinstock, and R.A. Gibbs. 2008. Analysis of transcriptome data in the red flour beetle, Tribolium castaneum. Insect Biochem. Mol. Biol. 38: 380-386.
PDF	Siebert, K.S., M.D. Lorenzen, S.J. Brown, Y. Park, and R.W. Beeman. 2008. Tubulin superfamily genes in Tribolium castaneum and the use of a tubulin promoter to drive transgene expression. Insect Biochem. Mol. Biol. 38: 749-755.
PDF	Tribolium Sequencing Consortium (includes R.W. Beeman, M.D. Lorenzen, B. Oppert, J. Lord, K. Kramer, Y. Arakane). 2008. The genome of the model beetle and pest Tribolium castaneum. Nature 452: 949-955.
PDF	Wang, S., M.D. Lorenzen, R.W. Beeman, and S.J. Brown. 2008. Analysis of repetitive DNA distribution patterns in the Tribolium castaneum genome. Genome Biol. 9: R61.
PDF	Lorenzen, M.D., T. Kimzey, T.D. Shippy, S.J. Brown, R.E. Denell, and R.W. Beeman. 2007. piggyBac-based insertional mutagenesis in Tribolium castaneum using donor/helper hybrids. Insect Mol. Biol. 16: 265-275.
PDF	Weinstock, G.M. ... Lorenzen, M.D. …. 2006. Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443: 931-959.
PDF	Arakane, Y., S. Muthukrishnan, K.J. Kramer, C.A. Specht, Y. Tomoyasu, M.D. Lorenzen, M. Kanost, and R.W. Beeman. 2005. The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix. Insect Mol. Biol. 14: 453-463.
PDF	Lorenzen, M.D., Z. Doyungan, J. Savard, K. Snow, L.R. Crumly, T.D. Shippy, J.J. Stuart, S.J. Brown, and R.W. Beeman. 2005. Genetic linkage maps of the red flour beetle, Tribolium castaneum, based on bacterial artificial chromosomes and expressed sequence tags. Genetics 170: 741-747.
PDF	Goodwin, T.J.D., R.T.M. Poulter, M.D. Lorenzen, and R.W. Beeman. 2004. DIRS retroelements in arthropods: identification of the recently active TcDirs1 element in the red flour beetle Tribolium castaneum. Mol. Genet. Genom. 272: 47-56.
PDF	Lorenzen, M.D., A.J. Berghammer, S.J. Brown, R.E. Denell, M. Klingler, and R.W. Beeman. 2003. piggyBac-mediated germline transformation in the beetle Tribolium castaneum. Insect Mol. Biol. 12: 433-440.
PDF	Lorenzen, M.D., S.J. Brown, R.E. Denell, and R.W. Beeman. 2002. Cloning and characterization of the Tribolium castaneum eye-color genes encoding tryptophan oxygenase and kynurenine 3-monooxygenase. Genetics 160: 225-234.
PDF	Lorenzen, M.D., S.J. Brown, R.E. Denell, and R.W. Beeman. 2002. Transgene expression from the Tribolium castaneum Polyubiquitin promoter. Insect Mol. Biol. 11: 399-407.
	Brown, S.J., Mahaffey, J.P., Lorenzen, M.D., Denell, R.E. and Mahaffey, J.W. 1999. Using RNAi to investigate orthologous homeotic gene function during development of distantly related insects. Evol. Biol. 1: 11–15.
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