Kartagener syndrome
Please note that the links contained on this search results page may take you
to sites outside of the NIH. (See Disclaimer under Site Policies for details.)
Kartagener syndrome is a type of primary ciliary dyskinesia associated with situs inversus totalis (mirror-image reversal of all visceral organs with no apparent physiologic consequence).[3] Kartagener syndrome is inherited in an autosomal recessive fashion and is characterized by the triad of situs inversus, bronchiectasis and sinusitis.[4] About 50% of individuals with primary ciliary dyskinesia have Kartagener syndrome.[1][2]
References
-
Primary Ciliary Dyskinesia. American Lung Association. May 2003 Available at: http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=2060321&content_id={480D5BF6-41F2-49C3-ADD4-D42666135FEE}¬oc=1. Accessed October 13, 2008.
-
Kartagener's Syndrome. Kartagener's Syndrome and Primary Ciliary Dyskinesia Foundation. Available at: http://www.kartagener-syndrom.org/html_english/erkrankung_definition.html. Accessed October 13, 2008.
-
Zariwala MA, Knowles MR, Leigh MW. Primary Ciliary Dyskinesia. GeneReviews. February 1, 2008 Available at: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=pcd. Accessed October 13, 2008.
-
Casanova MS, Tuji FM, Yoo HJ, Haiter-Neto F. . Dentomaxillofac Radiol. September 2006;:. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16940490. October 13, 2008.
For more information about Kartagener syndrome click on the boxes below:
Click arrows to expand or collapse a Resource Section.
Show All Resources
Hide All Resources
- More Information (Found: 6 Resources)
Links where you can find more general information, comprehensive resources, selected full text journal articles, and news updates
- General
-
eMedicine provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free
-
MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
-
The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
-
The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Kartagener syndrome. Click on the link to go to OMIM and review these resources.
-
PubMed lists journal articles that discuss Kartagener syndrome. Click on the link to go to PubMed and review citations to these articles.
- Management Guidelines
-
GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.
- Support Groups (Found: 8 Resources)
Groups providing a wide range of services, supportive resources, and information
- Umbrella Organizations
- Disease-Specific Organizations
- Live Chat
-
The National Organization of Rare Disorders (NORD) has partnered with Inspire.com to launch an online community for people with rare diseases called The NORD Rare Disease Community. This community connects medical patients, family members, caregivers, and professionals. Click on The NORD Rare Disease Community to learn more.
-
RareShare is an online social hub dedicated to patients, families and healthcare professionals affected by rare medical disorders. Click on RareShare to learn more.
- Research & Clinical Trials (Found: 3 Resources)
Resources where you may find research studies and clinical trials
-
CRISP is a searchable database of federally funded biomedical research projects conducted at universities, hospitals, and other research institutions. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies click on the link and enter the disease name in the enter search terms box and click the and button below the box. Then click Submit Query.
-
ClinicalTrials.gov lists trials that are studying or have studied Kartagener syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
-
The Genetic Disorders Of Mucociliary Clearance Consortium is a network of four U.S. centers (University of North Carolina at Chapel Hill, Washington University in St. Louis, University of Washington, and University of Colorado) that are collaborating in the diagnostic testing, genetic studies, and clinical trials in patients with impairments in mucociliary clearance, focusing on primary ciliary dyskinesia, cystic fibrosis, and pseudohypoaldosteronism. Ultimately, this group hopes to better define the clinical pathogenesis of these important airway diseases, improve or expand diagnostic testing, and develop new and effective treatments. To read more about this consortium and their involvement with primary ciliary dyskinesia and Kartagener syndrome, click on the above link.
- Services (Found: 1 Resources)
Links to Web sites that offer services, such as tools to locate specialists, specialty clinics, genetic services, and genetic testing laboratories
- Genetic Services
-
We recommend that you discuss this information and your concerns with a genetics professional. The following online resources can help you find a genetics professional in your community:
* GeneClinics - A searchable directory of US and international genetics and prenatal diagnosis clinics. To locate genetics clinics in the United States, go to the following link and click on 'Clinic Directory' to find a genetic service close to you.
* ResourceLink - A database of genetics counseling services, searchable by location, name, institution, type of practice, or specialty. Hosted by the National Society of Genetic Counselors.
- More Search Tools (Found: 1 Resources)
Resources to help you find more information on this topic
-
The NLM Gateway allows users to search across multiple resources offered on the National Library of Medicine's Web site. Some of these resources may be duplicated in the list of links above. Click on the link to go to the NLM Gateway, and search by condition name.