Osmond DH, Charlebois E, Page-Shafer K, Wiley J, Moss A, Sheppard H, Winkelstein W; International Conference on AIDS.
Int Conf AIDS. 1996 Jul 7-12; 11: 42 (abstract no. We.C.562).
Univ. of CA., San Francisco, CA. Fax: 415-476-0341.
Objective: To determine HIV incidence rates and risk behavior over time in a population-based cohort of young homosexual/bisexual men living in San Francisco California. Methods: A cohort of 428 young homosexual men were recruited by a probability household sample of single men ages 18-29 in 1992-93. An additional sample of 622 of their friends were recruited by referral during the first cycle of follow-up. Three follow-up examination cycles have been performed or are in progress (two with the referral sample). HIV incidence rates with 95% confidence intervals were calculated for each cycle separately for each sample and for both samples combined. Results: 17 men have seroconverted during follow-up. Mean follow-up times were 8.9 months 9.4 months and 16.6 months. Cycle 4 is in progress and results are preliminary (SC=seroconverter). (table: see text) The overlapping 95% confidence intervals leave in question whether these rates represent a real decline but there appears to be a trend toward lower rates. Conclusions: HIV infection rates appear to be declining in this cohort of young gay men. The preliminary current rates do not differ by sample and are below 1% per year not much different from rates previously reported in cohorts of older men. Declining rates in a closed cohort study may not accurately reflect community rates due to cohort effects of continued participation and testing and removal of high risk negatives. Whether this decline has been accompanied by a corresponding decline in high risk behavior remains to be determined.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Biomedical Research
- Bisexuality
- California
- Cohort Studies
- HIV
- HIV Antibodies
- HIV Infections
- HIV Seronegativity
- HIV Seropositivity
- HIV Seroprevalence
- Homosexuality
- Homosexuality, Male
- Humans
- Incidence
- Male
- Risk-Taking
- San Francisco
- Single Person
- immunology
Other ID:
UI: 102219191
From Meeting Abstracts