Awa N, Coll AM, Hane A, Seye I, Colebunders R, Sow S; International Conference on AIDS.
Int Conf AIDS. 1990 Jun 20-23; 6: 231 (abstract no. F.C.602).
Fann Hospital, Dakar, Senegal
OBJECTIVE: To determine the proportion of patients infected with HIV-1 and HIV-2 among patients visiting the infectious disease and tuberculosis wards of Fann Hospital, Dakar, Senegal. To compare results obtained in 1989 with those obtained during previous surveys in the same hospital. METHODS: In August 1989, all patients admitted to the infectious disease and the tuberculosis ward at Fann Hospital were screened for HIV. HIV testing was performed using the EIA Abott combi test HIV-1/HIV-2 and the following confirmatory tests: INNO LIA HIV-1/HIV-2 Ab (Innogenetics), Western blot HIV-1 (Dupont), New LAV blot II (Pasteur) and Pepti LAV 1 and 2 (Pasteur). RESULTS: Of the 210 patients screened in 1989, 20 (9%) were HIV (+) [14 males and 6 females (sex ratio:2.3)], 14 (7%) were HIV-1 (+), 4 (2%) HIV-2 (+) and 2 (1%) dually reactive to HIV-1 and HIV-2. This 9% HIV seroprevalence was significantly higher than the 1% seroprevalence observed in the same wards in 1987. The clinical WHO AIDS case definition had a sensitivity of 52%, a specificity of 95% and a positive predictive value of 50% for HIV seropositivity. CONCLUSION: Symptomatic HIV infection is an increasing problem among hospitalised patients in Dakar. In 1989 more hospitalised patients were infected with HIV-1 than with HIV-2. This is in contrast with previous findings among asymptomatic population groups in Senegal and suggests that HIV-1 is more pathogenic than HIV-2.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Female
- HIV Antibodies
- HIV Infections
- HIV Seropositivity
- HIV Seroprevalence
- HIV-1
- HIV-2
- Hospitals
- Humans
- Male
- Mass Screening
- Senegal
- Seroepidemiologic Studies
- Tuberculosis
Other ID:
UI: 102184531
From Meeting Abstracts