Mijch A, McGavin K, Dunne M, Birch C, Crowe S, Sebire K, Hoy J, Bryant M, DeGraaff B, Read R, Dax E; Australasian Society for HIV Medicine. Conference.
Annu Conf Australas Soc HIV Med. 1996 Nov 14-17; 8: 95 (abstract no. 104).
Alfred Hospital.
AIM: To describe the distribution of HIV plasma VL and CD4 cell count compared with clinical status of a cohort of HIV infected patients attending for outpatient treatment. To examine short-term outcome in relation to anti-retroviral exposure and VL. METHODS: VIDRL and MBC in collaboration with Fairfield Hospital began enrolling patients in an observational study in May 1995. In February 1996 a protocol for initial and 4 to 6 monthly follow-up VL assessments was introduced. RT-PCR was performed in 373 patients, 353 with CD4 and b-DNA in 34. Medical records were reviewed for clinical status and antiretroviral therapy. RT-PCR was performed using the Roche Amplicor method and b-DNA the Chiron methodology. RESULTS: VL and CD4 and proportion with ADI are tabulated for VL by RT-PCR and b-DNA groups [TABULAR DATA, SEE ABSTRACT VOLUME]. Type and duration of anti-retroviral therapy as well as 6 and 12 month ADI rate and mortality will be presented. CONCLUSION: In this group of patients with advanced HIV disease a single VL estimate correlates with CD4 cell and proportion with ADI. The relationship to short term survival will be determined.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Anti-HIV Agents
- Antigens, CD4
- CD4 Lymphocyte Count
- CD4-Positive T-Lymphocytes
- HIV
- HIV Infections
- HIV Long Terminal Repeat
- HIV Long-Term Survivors
- HIV Seropositivity
- Humans
- Plasma
- epidemiology
- genetics
- immunology
- organization & administration
Other ID:
UI: 102221940
From Meeting Abstracts