« Factbook Table of
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10. Research and Development Contracts
NHLBI Research and Development
Contract Obligations:* Fiscal Years 19972007
Text-only
With Data Points
* For detailed data on contract-supported clinical
trials, see Chapter 11.
NHLBI Total Research and Development Contract
Obligations: Fiscal Years 19972007
Dollars (Thousands)
|
FY 1997 |
FY 1998 |
FY 1999 |
FY 2000 |
FY 2001 |
FY 2002 |
FY 2003 |
FY 2004 |
FY 2005 |
FY 2006 |
FY 2007 |
Heart |
$ 84,820 |
$ 77,886 |
$156,370 |
$156,415 |
$184,491 |
$214,971 |
$258,647 |
$245,881 |
$219,796 |
$213,320 |
$260,205 |
Lung |
18,183 |
13,123 |
25,432 |
23,341 |
10,993 |
16,578 |
11,745 |
14,131 |
20,946 |
25,902 |
15,191 |
Blood |
18,934 |
25,695 |
15,436 |
21,538 |
24,572 |
26,751 |
20,082 |
25,460 |
27,831 |
23,629 |
20,446 |
Total |
$121,937A |
$116,704B |
$197,238C |
$201,294D |
$220,056E |
$258,300F |
$290,474G |
$285,472H |
$268,573I |
$262,851J |
$295,842K |
A Includes Program Evaluation and IMPAC II Assessments
of $8,986,000. B Includes Program Evaluation and IMPAC II Assessments of
$12,589,000. C Includes Program Evaluation and IMPAC II Assessments of
$14,904,000. D Includes Program Evaluation and IMPAC II Assessments of
$17,944,000. E Includes Program Evaluation and IMPAC II Assessments of
$24,579,000. F Includes Program Evaluation and IMPAC II Assessments of
$35,827,000. G Includes Program Evaluation and IMPAC II Assessments of
$54,550,000. H Includes Program Evaluation and IMPAC II Assessments of
$57,545,722. I Includes Program Evaluation and IMPAC II Assessments of
$64,399,000. J Includes Program Evaluation and IMPAC II Assessments of
$67,795,000. K Includes Program Evaluation and IMPAC II Assessments of
$68,405,000. Note: From 1999 to 2006 the WHI was reported separately. In
this table, it has been incorporated in the "Heart" line.
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Major NHLBI Research and
Development Contracts by Program
|
Total Obligations Prior
to FY 2007 |
Total FY 2007 Obligations |
Total Obligations to Date |
Heart and Vascular Diseases |
|
|
|
Atherosclerosis Risk in
Communities (ARIC) |
$128,310,450 |
$7,085,354 |
$135,395,804 |
Candidate Gene Association
Research (CARE) |
2,789,517 |
13,472,000 |
16,261,517 |
Cardiovascular Health Study
(CHS) |
76,816,177 |
355,000 |
77,171,177 |
Coronary Artery Risk
Development in Young Adults (CARDIA) |
78,720,161 |
3,519,585 |
82,239,746 |
DNA Resequencing and
Genotyping |
18,000,000 |
6,000,000 |
24,000,000 |
Framingham Heart
Study |
73,073,681 |
2,926,136 |
75,999,817 |
Genetically Triggered Thoracic
Aortic Aneurysms and OtherCardiovascular Conditions (GENTAC): National
Registry |
1,391,748 |
1,559,965 |
2,951,713 |
Hispanic Community Health
Study (HCHS) |
2,900,000 |
21,269,620 |
24,169,620 |
Jackson Heart Study
(JHS) |
23,755,565 |
4,346,757 |
28,102,322 |
Multi-Ethnic Study of
Atherosclerosis (MESA) |
62,833,704 |
5,833,988 |
68,667,692 |
NHLBI Gene Therapy Resource
Program (GTRP) |
|
5,900,000 |
5,900,000 |
Pediatric Circulatory
Support |
14,540,343 |
2,297,000 |
16,837,343 |
Proteomics
Initiative |
97,633,890 |
18,245,000 |
115,878,890 |
Registry for Mechanical
Circulatory Support |
2,801,579 |
946,139 |
3,747,718 |
SNP Health Association
Research (SHARE) |
2,000,000 |
9,172,820 |
11,172,820 |
Translational Behavioral
Science Research Consortium |
20,430,569 |
4,518,381 |
24,948,950 |
Lung Diseases |
|
|
|
Lung Tissue Research
Consortium |
23,098,806 |
|
23,098,806 |
Tuberculosis Curriculum
Coordinating Center |
4,875,000 |
|
4,875,000 |
Blood Diseases and
Resources |
|
|
|
Maintenance of Animals for
Hepatitis or AIDS Research |
8,966,004 |
466,117 |
9,432,121 |
Maintenance of NHLBI
Biological Specimen Repository |
7,625,914 |
2,181,239 |
9,807,153 |
Retrovirus Epidemiology Donor
Study II (REDS-II) |
95,820,174 |
8,437,846 |
104,258,020 |
Sickle Cell Disease
Health-Related Quality of Life Questionnaire |
1,292,008 |
179,000 |
1,471,008 |
Somatic Cell Therapy
Processing Facilities |
21,715,735 |
17,000 |
21,732,735 |
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Heart and Vascular Diseases
Program
Atherosclerosis Risk in Communities (ARIC), Initiated
in Fiscal Year 1985
The ARIC program is a large-scale, long-term program
that is measuring associations of CHD risk factors with atherosclerosis by
race, gender, and geographic location. It focuses on early detection of CVD
before symptoms, heart attacks, or strokes occur. The project consists of two
groups: a community surveillance component and a cohort component from four
communities. Three of the cohort components represent the racial mix of their
community, whereas the fourth is exclusively black.
In 2006, the study began conducting a community
surveillance of inpatients (ages ≥55 years) and outpatients (ages
≥65 years) who have heart failure. The study will continue through 2009
to determine the number of heart failure events occurring during the
20052009 period.
Obligations
Funding History: Fiscal Year 2007$7,085,354
Fiscal Years 19852006$128,310,450 Total Funding to
Date$135,395,804
Current Active Organizations and Contract
Numbers
- University of North Carolina at
Chapel Hill
Chapel Hill, North Carolina—HC-55015
- Baylor College of Medicine
Houston, Texas—HC-55016
- University of North Carolina at
Chapel Hill
Chapel Hill, North Carolina—HC-55018
- University of Minnesota, Twin Cities
Minneapolis, Minnesota—HC-55019
- Johns Hopkins University
Baltimore,
Maryland—HC-55020
- Mississippi Medical Center
Jackson,
Mississippi—HC-55021
Candidate Gene Association Resources (CARE),
Initiated in Fiscal Year 2006
This program establishes a genotyping and
bioinformatics center to perform high-throughput genotyping for candidate
gene association studies in up to 50,000 participants, and a genome-wide
association study in about 500 disease cases and 1,000 controls. The data will
be combined with available phenotype data to form a genotypephenotype
resource for public use. DNA for the 50,000-person sample will be collected
from multiple NHLBI cohort studies that have stored samples and available data
on a wide array of heart, lung, blood, and sleep phenotypes.
Obligations
Funding History: Fiscal Year 2007$13,472,000
Fiscal Year 2006$2,789,517 Total Funding to
Date$16,261,517
Current Active Organization and Contract Number
- Massachusetts Institute of Technology
Cambridge, Massachusetts—HC-65226
Cardiovascular Health Study (CHS), Initiated in
Fiscal Year 1988
The CHS is a population-based, longitudinal study of
risk factors for development and progression of CHS and stroke in elderly
adults, 17 percent of whom are from minority populations. Extensive data and
samples have been collected from nearly 6,000 participants since
19891990. The current CHS: Transition Phase is sharing support for an
infrastructure to enable continued access to study resources and expertise,
scientific collaborations, and mentorship of early-career investigators.
Obligations
Funding History: Fiscal Year 2007$355,000
Fiscal Years 19882006$76,816,177 Total Funding to
Date$77,171,177
Current Active Organization and Contract Number
- University of Washington
Seattle,
Washington—HC-55222
Coronary Artery Risk Development in Young Adults
(CARDIA), Initiated in Fiscal Year 1984
CARDIA is a long-term study examining the evolution of
CVD risk factors in a cohort of black and white adults, aged 18 to 30 years in
19851986. The study examines risk for heart and lung disease and diabetes
by collecting information on body mass index, physical activity and lifestyle,
genetics, serologic and metabolic components, inflammatory markers, and other
subclinical markers of disease. Fifty percent of the participants are
black.
Obligations
Funding History: Fiscal Year 2007$3,519,585
Fiscal Years 19842006$78,720,161 Total Funding to
Date$82,239,746
Current Active Organizations and Contract
Numbers
- New England Medical Center
Hospitals, Inc.
Boston, Massachusetts—HC-45204
- Wake Forest University Health Sciences
Winston-Salem, North Carolina—HC-45205
- University of Alabama at Birmingham
Birmingham,
Alabama—HC-48047
- University of Minnesota, Twin Cities
Minneapolis, Minnesota—HC-48048
- Northwestern University
Chicago, Illinois—HC-48049
- Kaiser Permanente Division of Research
Oakland,
California—HC-48050
- University of Alabama at Birmingham
Birmingham,
Alabama—HC-95095
DNA Resequencing and Genotyping, Initiated in Fiscal
Year 2004
The purpose of this program is to obtain rapid,
reliable, and cost-efficient DNA sequencing and genotyping of candidate genomic
regions potentially important in the disease pathways of heart, lung, and blood
diseases and sleep disorders. This information will assist ongoing
investigations of genetic components involved in the causes, variable outcome,
and progression of the diseases and disorders.
Obligations
Funding History: Fiscal Year 2007$6,000,000
Fiscal Years 20042006$18,000,000 Total Funding to
Date$24,000,000
Current Active Organizations and Contract
Numbers
- Constella Group, Inc.
Bethesda, Maryland—HV-48193
- University of Washington
Seattle,
Washington—HV-48194
- Johns Hopkins University
Baltimore,
Maryland—HV-48195
- J. Craig Venter Institute, Inc.
Rockville,
Maryland—HV-48196
Framingham Heart Study
The original Framingham Heart Study was designed as a
longitudinal investigation of constitutional and environmental factors
influencing the development of CVD in individuals free of these conditions at
the outset. Of the original 5,209 subjects, about 500 members remain alive. In
1971, the Framingham Offspring Study was initiated to assess familial and
genetic factors associated with CHD. More than 5,000 offspring (and their
spouses) were included. A third-generation cohort consisting of 3,500
grandchildren has been added to permit examination of numerous hypotheses about
the genetic contribution to CVD and CVD risk factors. Additional goals include
identifying new risk factors for cardiovascular, lung, and blood diseases and
developing new imaging tests that can detect very early stages of coronary
atherosclerosis in otherwise healthy adults.
Obligations
Funding History:
Fiscal Year 2007$2,926,136 Fiscal Years
19832006$73,073,681 Total Funding to Date$75,999,817
Current Active Organization and Contract Number
- Boston University Medical Center
Boston,
Massachusetts—HC-25195
Genetically Triggered Thoracic Aortic Aneurysms and
Other Cardiovascular Conditions (GENTAC): National Registry, Initiated in
Fiscal Year 2006
The purpose of this program is to establish a national
registry to enable investigators to determine the best medical practices to
advance the clinical management of genetic thoracic aortic aneurysms and other
cardiovascular complications associated with connective tissue diseases such as
Marfan Syndrome.
Obligations
Funding History: Fiscal Year 20071,559,965
Fiscal Year 2006$1,391,748 Total Funding to
Date$2,951,713
Current Active Organization and Contract Number
- Research Triangle Institute
Research Triangle
Park, North Carolina—HV-68199
Hispanic Community Health Study (HCHS), Initiated in
Fiscal Year 2006
The purpose of this study is to identify risk factors
for cardiovascular and lung diseases in Hispanic populations living in the
United States and determine the role of acculturation in their development and
prevalence. The program will support a multicenter, 6.5-year epidemiologic
study comprising approximately 16,000 participants of Hispanic origin (4,000 at
each of 4 sites), aged 18 to 74 years.
Obligations
Funding History: Fiscal Year 200721,269,620
Fiscal Year 2006$2,900,000 Total Funding to
Date$24,169,620
Current Active Organizations and Contract
Numbers
- University of North Carolina at
Chapel Hill
Chapel Hill, North Carolina—HC-65233
- University of Miami
Miami, Florida—HC-65234
- Albert Einstein College of Medicine
New York,
New York—HC-65235
- Northwestern University
Chicago, Illinois—HC-65236
- San Diego State University
San Diego,
California—HC-65237
Jackson Heart Study (JHS), Initiated in Fiscal Year
1998
The JHS is a single-site epidemiologic study of CVD in
blacks, similar to established studies in Framingham, Massachusetts, and
Honolulu, Hawaii, with primary goals of identifying risk factors for
development and progression of CVD; enhancing recruitment, cohort retention,
and scientific productivity of the existing Jackson site of the ARIC study;
building research capabilities at minority institutions; developing
partnerships between minority and majority institutions; and expanding minority
investigator participation in large-scale epidemiologic studies.
Obligations
Funding History: Fiscal Year 2007$4,346,757
Fiscal Years 19982006$23,755,565 Total Funding to
Date$28,102,322
Current Active Organizations and Contract
Numbers
- Jackson State University
Jackson,
Mississippi—HC-95170
- Mississippi Medical Center
Jackson,
Mississippi—HC-95171
- Tougaloo College
Tougaloo, Mississippi—HC-95172
Multi-Ethnic Study of Atherosclerosis (MESA),
Initiated in Fiscal Year 1999
The purpose of this study is to investigate the
prevalence, correlates, and progression of subclinical CVD, i.e., disease
detected noninvasively before it has produced clinical signs and symptoms, in a
population that is 38 percent white, 28 percent black, 22 percent Hispanic, and
12 percent Asian. In 2007, the fourth cohort examination was completed and
plans are underway to continue periodic monitoring of participants to identify
recent hospitalizations and other clinical events.
Obligations
Funding History: Fiscal Year 2007$5,833,988
Fiscal Years 19992006$62,833,704 Total Funding to
Date$68,667,692
Current Active Organizations and Contract
Numbers
- University of Washington
Seattle,
Washington—HC-95159
- University of California, Los Angeles
Los
Angeles, California—HC-95160
- Columbia University
New York, New York—HC-95161
- Johns Hopkins University
Baltimore,
Maryland—HC-95162
- University of Minnesota, Twin Cities
Minneapolis, Minnesota—HC-95163
- Northwestern University
Chicago, Illinois—HC-95164
- Wake Forest University
Winston-Salem, North
Carolina—HC-95165
- University of Vermont
Colchester, Vermont—HC-95166
- New England Medical Center
Boston,
Massachusetts—HC-95167
- Johns Hopkins University
Baltimore,
Maryland—HC-95168
- Harbor-UCLA Research and
Education
Institute Los Angeles, California—HC-95169
NHLBI Gene Therapy Resource Program (GTRP), Initiated
in Fiscal Year 2007
The purpose of this program is to promote the
translation of basic research into clinical trials. The
program will support the production of safe and well-characterized
vectors; conduct extensive toxicology and pharmacology studies on animals to
determine vector dosing, related toxicity, and vector dissemination; and
provide investigators with regulatory assistance to initiate a clinical
trial. The GTRP also will support a maximum of two phase I/II gene transfer
clinical trials per year that have successfully met all regulatory requirements
and are ready to enroll patients within 12 months of application
approval.
Obligations
Funding History: Fiscal Year 2007$5,900,000
Total Funding to Date$5,900,000
Current Active Organizations and Contract
Numbers
- Social and Scientific Systems, Inc.
Silver
Spring, Maryland—HV-78200
- Lovelace Biomedical Research &
Education
Institute Albuquerque, New Mexico—HV-78201
- University of Pennsylvania
Philadelphia,
Pennsylvania—HV-78202
- Childrens Hospital of Philadelphia
Philadelphia, Pennsylvania—HV-78203
- Indiana University
Indianapolis, Indiana—HV-78204
Pediatric Circulatory Support, Initiated in Fiscal
Year 2004
The purpose of this program is to establish
multidisciplinary teams to develop innovative circulatory assist devices or
other bioengineered systems for infants and children with congenital and
acquired CVD who experience cardiopulmonary failure and circulatory
collapse.
Obligations
Funding History: Fiscal Year 2007$2,297,000
Fiscal Years 20042006$14,540,343 Total Funding to
Date$16,837,343
Current Active Organizations and Contract
Numbers
- Cleveland Clinic
Lerner College of
Medicine Cleveland, Ohio—HV-48188
- Ension, Inc.
Pittsburgh, Pennsylvania—HV-48189
- Jarvik Heart, Inc.
New York, New York—HV-48190
- Pennsylvania State University
Hershey,
Pennsylvania—HV-48191
- University of Pittsburgh
Pittsburgh,
Pennsylvania—HV-48192
Proteomics Initiative, Initiated in Fiscal Year
2002
The purpose of this program is to establish highly
interactive, multidisciplinary centers to enhance and develop innovative
proteomic technologies directed to relevant biologic questions associated with
heart, lung, blood, and sleep health and disease. Scientists will focus on the
cells protein machinery directed toward understanding the molecular basis
of the causes and progression of heart, lung, and blood diseases and sleep
disorders and identifying targets for therapeutic interventions.
Obligations
Funding History: Fiscal Year 2007$18,245,000
Fiscal Years 20022006$97,633,890 Total Funding to
Date$115,878,890
Current Active Organizations and Contract
Numbers
- Boston University
Boston, Massachusetts—HV-28178
- Institute for Systems Biology
Seattle,
Washington—HV-28179
- Johns Hopkins University
Baltimore,
Maryland—HV-28180
- Medical University of South Carolina
Charleston, South Carolina—HV-28181
- Medical College of Wisconsin
Milwaukee,
Wisconsin—HV-28182
- Stanford University
Stanford, California—HV-28183
- University of Texas
Galveston, Texas—HV-28184
- University of Texas
Southwestern Medical
Center Dallas, Texas—HV-28185
- Yale University
New Haven, Connecticut—HV-28186
- Henry M. Jackson Foundation for the
Advancement of Military Medicine, Inc. Rockville, Maryland—HV-28187
Registry for Mechanical Circulatory Support,
Initiated in Fiscal Year 2005
The purpose of this program is to establish a data and
clinical coordinating center to manage a registry of patients receiving a
mechanical circulatory support device (MCSD) to treat heart failure. The
registry will collect and analyze clinical and laboratory data and tissue
samples from patients who receive MCSDs as destination therapy for end-stage
heart failure at 60 to 70 participating hospitals.
Obligations
Funding History: Fiscal Year 2007$946,139
Fiscal Years 20052006$2,801,579 Total Funding to
Date$3,747,718
Current Active Organization and Contract Number
- University of Alabama
Birmingham, Alabama—HV-58198
SNP Health Association Resource (SHARe), Initiated in
Fiscal Year 2006
The purpose of this program is to identify genetic
variants associated with heart, lung, and blood diseases and sleep disorders
through application of large-scale, single nucleotide polymorphism (SNP)
genotyping for genome-wide association analyses. In collaboration with the
National Center for Biotechnology Information, the Institute is developing a
public-use data resource to integrate genome-wide genotypic information with
phenotypic information from multiple NHLBI studies. The first study involves
more than 14,000 participants in the Framingham Heart Study. Genotype and
phenotype data from the study will be available to qualified and approved
applicants beginning October 1, 2007. Two studies will be added in 2008 and
2009.
Obligations
Funding History: Fiscal Year 2007$9,172,820
Fiscal Year 2006$2,000,000 Total Funding to
Date$11,172,820
Current Active Organization and Contract Number
- Affymetrix, Inc.
Santa Clara, California—HL-64278
Translational Behavioral Science Research Consortium,
Initiated in Fiscal Year 2002
The purpose of this program is to establish a
consortium of interdisciplinary basic and applied social scientists to conduct
research related to developing and testing theories from the behavioral or
social sciences concerning cognitive, affective, motivational, developmental,
and other factors and processes underlying human behavior. Acquired knowledge
will be used to develop and test methods to encourage individuals to adopt and
maintain a healthy lifestyle and manage behavioral risk factors for heart,
lung, and blood diseases and sleep disorders.
Obligations
Funding History: Fiscal Year 2007$4,518,381
Fiscal Years 20022006$20,430,569 Total Funding to
Date$24,948,950
Current Active Organizations and Contract
Numbers
- Weill Medical College of
Cornell University
New York, New York—HC-25196
- Mount Sinai School of Medicine
New York, New
York—HC-25197
Lung Diseases Program
Lung Tissue Research Consortium, Initiated in Fiscal
Year 2004
The purpose of this program is to establish a
consortium for collecting lung tissues and preparing and distributing them for
research. Scientists seek to improve management of lung diseases by increasing
understanding of the pathogenetic mechanisms of lung diseases through molecular
histopathological studies on tissues with and without disease. Primary emphases
are on COPD and idiopathic pulmonary fibrosis.
Obligations
Funding History: Fiscal Year 2007$0
Fiscal Years 20042006$23,098,806 Total Funding to
Date$23,098,806
Current Active Organizations and Contract
Numbers
- Mayo Clinic College of Medicine
Rochester, New
York—HR-46158
- University of Colorado
Health Science
Center Denver, Colorado—HR-46159
- University of Colorado
Health Science
Center Denver, Colorado—HR-46160
- Mayo Clinic College of Medicine
Rochester, New
York—HR-46161
- University of Michigan
Ann Arbor, Michigan—HR-46162
- University of Pittsburgh
Pittsburgh,
Pennsylvania—HR-46163
- Clinical Trials and Survey Corporation
Baltimore, Maryland—HR-46164
Tuberculosis Curriculum Coordinating Center,
Initiated in Fiscal Year 2003
The purpose of this program is to establish a
consortium of five Tuberculosis Curriculum Centers to strengthen and
increase access to the best ongoing educational and training
opportunities in TB for medical, nursing, and allied health schools, especially
those that provide primary care to communities where TB is endemic and the
population is at high risk.
Obligations
Funding History: Fiscal Year 2007$0
Fiscal Years 20032006$4,875,000 Total Funding to
Date$4,875,000
Current Active Organization and Contract Number
- University of California, San Diego
La Jolla,
California—HR-36157
Blood Diseases and Resources
Program
Maintenance of Animals for Hepatitis or AIDS
Research, Initiated in Fiscal Year 1992
The purpose of this program is to maintain an NHLBI
chimpanzee colony that can be used in experiments with transfusion-transmitted
infectious agents (hepatitis C virus (HCV), hepatitis B virus (HBV), and
HIV) for which the chimpanzee is the only known animal model.
Obligations
Funding History: Fiscal Year 2007$466,117
Fiscal Years 19922006$8,966,004 Total Funding to
Date$9,432,121
Current Active Organization and Contract Number
- Southwest Foundation for
Biomedical
Research San Antonio, Texas—HB-27091
Maintenance of NHLBI Biological Specimen Repository,
Initiated in Fiscal Year 1998
The purpose of this project is to establish an NHLBI
Biological Specimen Repository for blood specimens from Institute-supported
research. The Repository monitors storage, labeling, and testing of the
specimens, as well as administers safe shipment of precise sample aliquots to
approved investigators for future studies.
Obligations
Funding History: Fiscal Year 2007$2,181,239
Fiscal Years 19982006$7,625,914 Total Funding to
Date$9,807,153
Current Active Organization and Contract Number
- SeraCare Life Sciences, Inc.
Rockville,
Maryland—HB-87144
Retrovirus Epidemiology Donor Study (REDS), Initiated
in Fiscal Year 1989
The purpose of this study is to conduct epidemiologic,
laboratory, and survey research on volunteer blood donors within the United
States to ensure the safety and availability of the blood supply. The studies
will examine the risks of transfusion-transmissible infections, their trends,
and ways to reduce infection risks; HIV, HTLV, HCV, and HBV test screening
methodologies; donor characteristics, behaviors, and donation return patterns
of U.S. blood donors; and the effectiveness and safety of various strategies to
increase the U.S. blood supply. An international component has been added to
the REDS study to conduct epidemiologic, laboratory, and survey research on the
blood donors in China and Brazil.
Obligations
Funding History: Fiscal Year 2007$8,437,846
Fiscal Years 19892006$95,820,174 Total Funding to
Date$104,258,020
Current Active Organizations and Contract
Numbers
- Blood Center of Southeastern Wisconsin
Milwaukee, Wisconsin—HB-47168
- American Red Cross Blood Service,
New
England Farmington, Connecticut—HB-47169
- Emory University
Atlanta, Georgia—HB-47170
- University of Cincinnati
Cincinnati, Ohio—HB-47171
- Institute for Transfusion Medicine
Pittsburgh,
Pennsylvania—HB-47172
- University of California, San Francisco
San
Francisco, California—HB-47174
- Westat, Inc.
Rockville, Maryland—HB-47175
- Blood System Research, Inc.
San Francisco,
California—HB-57181
Sickle Cell Disease Health-Related Quality of Life
Questionnaire, Initiated in Fiscal Year 2005
The purpose of this project is to develop a
psychometrically sound and clinically useful health-related quality-of-life
instrument and related materials for use in sickle cell clinical trials and
outcomes research among adults with SCD, and to assist researchers who are
early users of the instrument and materials.
Obligations
Funding History: Fiscal Year 2007$179,000
Fiscal Years 20052006$1,292,008 Total Funding To
Date$1,471,008
Current Active Organization and Contract Number
- American Institutes for Research
Health
Program Silver Spring, Maryland—HL-54264
Somatic Cell Therapy Processing Facilities, Initiated
in Fiscal Year 2003
This program is designed to develop novel somatic
cellular therapies in areas ranging from basic science through animal studies
to proof-of-principle and eventually human trials for heart, lung, and blood
diseases and sleep disorders. The goal is to provide rapid, safe
translation of basic research ideas into clinical practice.
Obligations
Funding History: Fiscal Year 2007$17,000
Fiscal Years 20032006$21,715,735 Total Funding to
Date$21,732,735
Current Active Organizations and Contract
Numbers
- Baylor College of Medicine
Houston, Texas—HB-37163
- University of Minnesota, Twin Cities
Minneapolis, Minnesota—HB-37164
- University of Pittsburgh
Pittsburgh,
Pennsylvania—HB-37165
- The EMMES Corporation
Rockville, Maryland—HB-37166
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