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Nuclear Structure-Function Defects in the Pathogenesis of Muscular Dystrophy (R21)
Release Date: April 14, 2006
Announcement Number: RFA-NS-07-002
Application Receipt Date:
September 20, 2006
Letter of Intent Date: August 21, 2006
Funding Contact: John Porter, Ph.D.
Program Area: Channels, Synapses and Neural Circuits
Brief Description:
This funding announcement (FOA) solicits Exploratory/Developmental (R21) grant applications from applicant organizations that
propose to identify the mechanisms of a subset of muscular dystrophies that may have their basis in nucleus structure-function
defects. Applications are specifically solicited for studies of Emery-Dreifuss, facioscapulohumeral, limb girdle muscular
dystrophy 1B, and oculopharyngeal muscular dystrophies. Applications for studies of other muscular dystrophies are not responsive
to this RFA. The expected outcomes are improvements in understanding of the genetic, cell, and molecular mechanisms of these
muscular dystrophies. Applicants who can bring knowledge and expertise in the biology of the nucleus to studies of disease
mechanisms are particularly encouraged.
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