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Application processes at NIH are changing. Applicant organizations are encouraged to start preparing for this transition by registering with Grants.gov and NIH eRA Commons now.

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Structural Biology of Membrane Proteins (R01)
Release Date: January 20, 2006
Announcement Number: PA-06-119
Application Receipt Date:
February 1, 2006
June 1, 2006
October 1, 2006   

Funding Contact: Randall Stewart, Ph.D.
Program Area: Channels, Synapses and Neural Circuits

Brief Description:
This PA solicits applications to develop research and methods to enhance the rate of membrane protein structure determination and to determine specific membrane protein structures. Innovative methods for expression, oligomerization, solubilization, stabilization, purification, characterization, crystallization, isotopic labeling, and structure determination of unique and biologically significant membrane proteins by x-ray diffraction, nuclear magnetic resonance (NMR), electron microscopic, mass spectrometry, and other biophysical techniques are encouraged. Projects that will lead in the near term to determining the structures of biologically important membrane proteins are also encouraged.

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