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Developing the Potential of Xenopus Tropicalis as a Genetic Model
Release Date: January 31, 2001
Announcement Number: RFA-HD-01-008
Application Receipt Date:
July 11, 2001
Letter of Intent Date: May 16, 2001
Funding Contact: NINDS Funding
Program Area: Neurogenetics
Brief Description:
This Request for Applications (RFA) solicits research grant applications to examine the feasibility of using Xenopus tropicalis
for standard genetic manipulations. The research proposed should optimize the conditions required to perform efficient, large-scale
mutagenesis, and should use the optimized parameters to perform small-scale mutagenesis; phenotyping; and gene cloning, identification,
and characterization. Mutant animals, protocols, and data produced by these projects should be made available to the scientific
community. We anticipate that the mutants, data and procedures developed by the projects funded under this RFA will enable
Xenopus tropicalis to play a significant role in identifying and characterizing genes that regulate cellular and developmental
processes.
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