NINDS Neuroscience Funding Announcements

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Development and Improvement of Inbred ES Cell Lines for Use in Generation of Mouse Mutants
Release Date: September 16, 2005
Announcement Number: RFA-DA-06-009
Application Receipt Date:
November 22, 2005   
Letter of Intent Date: October 20, 2005

Funding Contact: Robert RiddlePh.D.
Program Area: Neurogenetics
Also See:  http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-05-007.html

Brief Description:
The purpose of this RFA is to develop C57BL/6 ES cell lines that are efficient for high-throughput gene targeting and in successfully generating mice that can transmit the targeted mutation through the germline, both steps being necessary to create knockout mice on a C57BL/6 background. This RFA is a companion to two other RFAs (HG-05-007 and HG-05-008), all three of which are part of the NIH Knockout Mouse Project (KOMP).

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