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nabilone
A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | Cpd 109514 | | | | Foreign brand name: | | Cesamet | | |
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