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fentanyl sublingual spray A sublingual preparation of a short-acting, synthetic anilidopiperidine opioid with analgesic activity. After rapid sublingual transmucosal absorption, the active ingredient fentanyl selectively binds to and activates mu-opioid receptors in the central nervous system (CNS), mimicking the effects of endogenous opiates. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20081025091143im_/http://www.cancer.gov/images/spacer.gif) | fentanyl SL spray | | ![](https://webarchive.library.unt.edu/eot2008/20081025091143im_/http://www.cancer.gov/images/spacer.gif) |
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