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formestane
A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | 4-hydroxyandrostenedione | | | | Foreign brand name: | | Lentaron | | | | Abbreviations: | | 4-OHA
4-OHAD | | | | Code name: | | CGP-32349 | | | | Chemical structure name: | | 4-Hydroxyandrost-4-ene-3,17-dione | | |
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