 |
|
mitotane
A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Chloditan
Chlodithane
Khloditan
Mytotan
o,p'-DDD
Ortho,para-DDD | | | | US brand name: | | Lysodren | | | | Foreign brand name: | | Lisodren | | | | Abbreviations: | | DDD
o,p' - DDD | | | | Code names: | | CB-313
WR-13045 | | | | Chemical structure names: | | - 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
- 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
- 2-(2-chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane
- 2,2-bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane
- 2,4'-dichlorodiphenyldichloroethane
| | |
|
|
