 |
|
levothyroxine sodium
The sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | Therapeutic Levothyroxine | | | | US brand names: | | Levoxyl
Synthroid | | |
|
|
