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Last Modified: 5/7/2008


1.		Phase III Randomized Study of High Versus Standard Dose Methotrexate and High Dose Cytarabine and Asparaginase Rescue Versus Standard Dose Cytarabine and Teniposide During Intensive Continuation and Consolidation in Children with High Risk Acute Lymphocytic Leukemia: An ALinC #16 Study

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				1 to 21 at diagnosis				NCI				POG-9406 POG-ALINC-16/HR, POG-9406

Last Modified: 5/24/2006


2.		Phase III Randomized Study of Bone Marrow Transplantation vs Prolonged Intensive Chemotherapy Following Remission Re-Induction after Early First Marrow Relapse in Children with Acute Lymphocytic Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				at least 1 + under 20 at diag.				NCI				CCG-1941 CCG-1941

Last Modified: 12/20/2007


3.		Phase III Randomized Study of Oral Mercaptopurine vs Oral Thioguanine and of Intrathecal MTX vs Triple Intrathecal Chemotherapy (Methotrexate, Catarabine, and Hydrocortisone) During Consolidation, Interim Maintenance, and Maintenance for Newly Diagnosed Standard Risk Childhood Acute Lymphoblastic Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				1 to 9				NCI				CCG-1952 NCT00002744, CCG-1952

Last Modified: 8/10/2006


4.		Phase III Randomized Study of Induction With the ALL-2 Regimen (Cytarabine and High-Dose Mitoxantrone Based) Versus the L-20 Regimen (Vincristine and Prednisone Based) in Adults With Acute Lymphoblastic Malignancy: The ALL-4 Protocol

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				18 and over				Other				MSKCC-96015A1 NCI-V96-0881, NCT00002766

Last Modified: 9/26/2008 First Published: 10/1/1996


5.		Phase III Randomized Study of Treatment Based on Response to Induction Chemotherapy in Patients With Higher Risk Childhood Acute Lymphocytic Leukemia: Standard Versus Augmented Berlin-Frankfurt-Munster Regimen With Standard Versus Prolonged Intensification For Rapid Early Responders and Doxorubicin Versus Idarubicin and Cyclophosphamide With Delayed Intensification For Slow Early Responders

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				1 to 21				NCI				CCG-1961 NCT00002812, CCG-1961

Last Modified: 1/1/2001 First Published: 10/1/1996


6.		Phase III Study of Systemic Chemotherapy Combined with Local Therapy for Isolated Extramedullary Relapse of Acute Lymphoblastic Leukemia (Summary Last Modified 01/2001)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				under 21				NCI				CCG-1951 NCT00002816, CCG-1951

Last Modified: 12/14/2006 First Published: 10/1/1998


7.		Phase III Randomized Study of Prednisolone Versus Dexamethasone and Mercaptopurine Versus Thioguanine in Children With Acute Lymphoblastic Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				1 to 18				Other				MRC-LEUK-ALL97 EU-97032, NCT00003437

Last Modified: 6/16/2008 First Published: 5/1/2000


8.		Phase III Randomized Study of Methotrexate With or Without Delayed Intensification in Patients With Low-Risk Acute Lymphoblastic Leukemia: AlinC #17

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				1 to 9				NCI				COG-P9904 POG-9904, NCT00005585

Last Modified: 6/16/2008 First Published: 5/1/2000


9.		Phase III Randomized Study of Multidrug Delayed-Intensification Therapy in Children With Newly Diagnosed Standard-Risk Acute Lymphocytic Leukemia: An ALinC #17 Study

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				1 to 21 at diagnosis				NCI				COG-P9905 POG-9905, NCT00005596

Last Modified: 8/15/2008 First Published: 7/1/2000


10.		Phase III Randomized Study of Escalating-Dose Intravenous Methotrexate Without Leucovorin Calcium Versus Oral Methotrexate and Single Versus Double Delayed Intensification in Children With Acute Lymphoblastic Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				1 to 9				NCI				COG-C1991 CCG-1991, NCT00005945

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