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monoclonal antibody Me1-14 F(ab')2 The F(ab)2 fragment of Me1-14, a murine IgG2a monoclonal antibody directed against proteoglycan chondroitin sulfate-associated protein expressed by gliomas and melanomas. By binding to proteoglycan chondroitin sulfate-associated protein, monoclonal antibody Me1-14 F(ab')2 conjugated to a radioisotope may localize gliomas and melanomas when used as a tracer in radioimaging applications; in radioimmunotherapeutic applications, this agent conjugated to a radioisotope may be used to deliver targeted radiotoxicity to these tumors. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym: | | Me1-14 F(ab')2 | | | Abbreviation: | | MOAB Me1-14 F(ab')2 | | |
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