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matuzumab A humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor receptor (EGFR) with high
affinity, competitively blocking natural ligand binding and
blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Code name: | ![](https://webarchive.library.unt.edu/eot2008/20081025012211im_/http://www.cancer.gov/images/spacer.gif) | EMD 72000 | | ![](https://webarchive.library.unt.edu/eot2008/20081025012211im_/http://www.cancer.gov/images/spacer.gif) |
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