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ammonium tetrathiomolybdate An ammonium salt with potential antiangiogenic and antitumor activities. Tetrathiomolybdate has been found to deplete systemic copper reserves through an unknown mechanism. This agent has been shown to inhibit the activities of cuproenzymes, including superoxide dismutase 1 (SOD1) and cytochrome c oxidase (COX), which may contribute to its antiangiogenic and antitumor effects. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081024150708im_/http://www.cancer.gov/images/spacer.gif) | tetrathiomolybdate | | ![](https://webarchive.library.unt.edu/eot2008/20081024150708im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20081024150708im_/http://www.cancer.gov/images/spacer.gif) | ammonium TM ATM ATTM | | ![](https://webarchive.library.unt.edu/eot2008/20081024150708im_/http://www.cancer.gov/images/spacer.gif) |
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