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demineralized bone matrix
Demineralized allograft bone with osteoinductive activity. Demineralized
bone matrices are prepared by acid extraction of allograft
bone, resulting in loss of most of the mineralized component
but retention of collagen and noncollagenous proteins, including
growth factors.
The efficacy of a demineralized
bone matrix (DBM) as a bone-graft substitute or extender may be related to the total amount of bone morphogenetic
protein (BMP) present, and the ratios of the different BMPs
present. BMPs belong to the transforming growth factor (TGF) superfamily of proteins. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Acronym: | | DBM | | |
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