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Phase of Trial
Title
Type of Trial
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Protocol IDs
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1.
Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Active
18 to 59
Other
N06IAA
NCT00448266
Last Modified:
6/9/2008
 
First Published:
9/26/2007
2.
Phase II/III Study of Disease-Specific High-Dose Conditioning Regimens Followed by Autologous Stem Cell Transplantation (Single or Tandem) in Patients With Hematologic Malignancies or Solid Tumors
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Active
4 and over
NCI
RPCI-I-72806
I 72806, NCT00536601
3.
Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III, Phase II
Treatment
Active
0 to 30
Other
EUDRACT 2005-002618-40
BfArM-4030755, EC-105/05, DKS 2006.01, NCT00749723
Last Modified:
9/19/2008
 
First Published:
6/2/2006
4.
Phase III Randomized Study of Induction Chemotherapy Comprising Vincristine, Etoposide, Cyclophosphamide, and Cisplatin With or Without High-Dose Methotrexate and Leucovorin Calcium Followed by Consolidation Chemotherapy Comprising Carboplatin and Thiotepa and Peripheral Blood Stem Cell Rescue in Pediatric Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Biomarker/Laboratory analysis, Treatment
Active
Under 3
NCI
COG-ACNS0334
ACNS0334, NCT00336024
Last Modified:
9/9/2008
 
First Published:
9/23/2006
5.
Phase III Randomized Study of Graft-Versus-Host Disease Prophylaxis Comprising Tacrolimus and Methotrexate With or Without Sirolimus in Pediatric Patients With Intermediate-Risk or High-Risk Acute Lymphoblastic Leukemia in Second Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Supportive care, Treatment
Active
1 to 21 at first relapse
NCI
COG-ASCT0431
ASCT0431, COG-PBMTC-ONCO51, NCT00382109
Last Modified:
6/11/2008
 
First Published:
10/21/2006
6.
Phase III Pilot Study of Induction Chemotherapy Followed by Consolidation Myeloablative Chemotherapy Comprising Thiotepa and Carboplatin With or Without Etoposide and Autologous Hematopoietic Stem Cell Rescue in Pediatric Patients With Previously Untreated Malignant Brain Tumors
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Active
Under 10 at diagnosis
Other
CHLA-HEAD-START-III
CHLA-HSIII, CHLA-2004-020, CHLA-04.020, NCT00392886, UMN-MT2004-06
Last Modified:
9/18/2008
 
First Published:
3/16/2007
7.
Phase III Randomized Study of Filgrastim (G-CSF)-Stimulated Allogeneic Bone Marrow Transplantation Versus Conventional Bone Marrow Transplantation in Pediatric Patients With Hematologic Cancer or Other Diseases
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Active
Under 22
NCI
COG-ASCT0631
ASCT0631, COG-PBMTC-STC051, NCT00450450
Last Modified:
9/5/2008
 
First Published:
11/2/2007
8.
Phase III Study of Multimodality Therapy Comprising Induction Chemotherapy, High-Dose Consolidation Chemotherapy, Autologous Stem Cell Transplantation, and/or Radiotherapy in Children With Extraocular Retinoblastoma
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Active
10 and under
NCI
COG-ARET0321
ARET0321, NCT00554788
Last Modified:
9/19/2008
 
First Published:
12/3/2007
9.
Phase III Randomized Study of Single Versus Tandem Myeloablative Consolidation Therapy Followed by Peripheral Blood Stem Cell Transplantation in Young Patients With High-Risk Neuroblastoma
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Biomarker/Laboratory analysis, Treatment
Active
30 and under
NCI
COG-ANBL0532
ANBL0532, NCT00567567
Last Modified:
8/25/2008
 
First Published:
4/2/2008
10.
Phase III Study of Induction Therapy Comprising Vincristine, High-Dose Methotrexate, Leucovorin Calcium, Etoposide, Cisplatin, and Cyclophosphamide Followed by 3-Dimensional Conformal Radiotherapy and High-Dose Consolidation Therapy Comprising Carboplatin, Thiotepa, and Autologous Peripheral Blood Stem Cell Rescue in Pediatric Patients With Atypical Teratoid/Rhabdoid Tumors of the Central Nervous System
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Biomarker/Laboratory analysis, Treatment
Approved-not yet active
21 and under at the time of definitive surgery
NCI
COG-ACNS0333
ACNS0333, NCT00653068
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