National Cancer Institute National Cancer Institute
U.S. National Institutes of Health National Cancer Institute
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What You Need To Know About™ Liver Cancer
    Posted: 02/08/2002    Updated: 09/16/2002
The Promise of Cancer Research

Laboratory scientists are studying the liver to learn more about what may cause liver cancer and how liver cancer cells work. They are looking for new therapies to kill cancer cells.

Doctors in hospitals and clinics are conducting many types of clinical trials. These are research studies in which people take part voluntarily. In these trials, researchers are studying ways to treat liver cancer that have shown promise in laboratory studies. Research has led to advances in treatment methods, but controlling liver cancer remains a challenge. Scientists continue to search for more effective ways to treat this disease.

Patients who join clinical trials have the first chance to benefit from new treatments. They also make an important contribution to medical science. Although clinical trials may pose some risks, researchers take very careful steps to protect people.

Currently, clinical trials involve chemotherapy, chemoembolization, and radiofrequency ablation for the treatment of liver cancer. Another approach under study is biological therapy, which uses the body's natural ability (immune system) to fight cancer. Biological therapy is being studied in combination with chemotherapy.

Patients who are interested in joining a clinical study should talk with their doctor. They may want to read the NCI booklet Taking Part in Cancer Treatment Research Studies 1. It explains how clinical trials are carried out and explains their possible benefits and risks. NCI's Web site at http://www.cancer.gov provides general information about clinical trials. It also offers detailed information about specific ongoing studies of liver cancer by linking to PDQ®, 2 NCI's cancer information database. The Cancer Information Service at 1-800-4-CANCER can answer questions about cancer clinical trials and can provide information from the PDQ database.



Glossary Terms

biological therapy (BY-oh-LAH-jih-kul THAYR-uh-pee)
Treatment to boost or restore the ability of the immune system to fight cancer, infections, and other diseases. Also used to lessen certain side effects that may be caused by some cancer treatments. Agents used in biological therapy include monoclonal antibodies, growth factors, and vaccines. These agents may also have a direct antitumor effect. Also called immunotherapy, biotherapy, biological response modifier therapy, and BRM therapy.
immune system (ih-MYOON SIS-tem)
The complex group of organs and cells that defends the body against infections and other diseases.


Table of Links

1http://cancer.gov/clinicaltrials/Taking-Part-in-Cancer-Treatment-Research-Studi
es
2http://cancer.gov/cancertopics/pdq